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dc.contributor.authorSen, Taner
dc.contributor.authorAstarcioglu, Mehmet Ali
dc.contributor.authorBeton, Osman
dc.contributor.authorAsarcikli, Lale Dinc
dc.contributor.authorKilit, Celal
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:44:00Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:44:00Z
dc.date.issued2017
dc.identifier.issn0066-782X
dc.identifier.urihttps://dx.doi.org/10.5935/abc.20170003
dc.identifier.urihttps://hdl.handle.net/20.500.12418/6852
dc.descriptionWOS: 000397928500009en_US
dc.descriptionPubMed ID: 28099589en_US
dc.description.abstractBackground: According to common belief, most myocardial infarctions (MIs) are due to the rupture of nonsevere, vulnerable plaques with < 70% obstruction. Data from recent trials challenge this belief, suggesting that the risk of coronary occlusion is, in fact, much higher after severe stenosis. The aim of this study was to investigate whether or not acute ST-elevation MIs result from high-grade stenoses by evaluating the presence of coronary collateral circulation (CCC). Methods: We retrospectively included 207 consecutive patients who had undergone primary percutaneous coronary intervention for acute ST-elevation MI. Collateral blood flow distal to the culprit lesion was assessed by two investigators using the Rentrop scoring system. Results: Out of the 207 patients included in the study, 153 (73.9%) had coronary collateral vessels (Rentrop 1-3). The Rentrop scores were 0, 1, 2, and 3 in 54 (26.1%), 50 (24.2%), 51 (24.6%), and 52 (25.1%) patients, respectively. Triglycerides, mean platelet volume (MPV), white cell (WBC) count, and neutrophil count were significantly lower in the group with good collateral vessels (p = 0.013, p = 0.002, p = 0.003, and p = 0.021, respectively). Conclusion: More than 70% of the patients with acute MI had CCC with Rentrop scores of 1-3 during primary coronary angiography. This shows that most cases of acute MI in our study originated from underlying high-grade stenoses, challenging the common believe. Higher serum triglycerides levels, greater MPV, and increased WBC and neutrophil counts were independently associated with impaired development of collateral vessels.en_US
dc.language.isoengen_US
dc.publisherARQUIVOS BRASILEIROS CARDIOLOGIAen_US
dc.relation.isversionof10.5935/abc.20170003en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPlaqueen_US
dc.subjectAtheroscleroticen_US
dc.subjectRuptureen_US
dc.subjectMyocardial Infarctionen_US
dc.subjectCoronary Restenosisen_US
dc.subjectCollateral Circulationen_US
dc.titleWhich Coronary Lesions Are More Prone to Cause Acute Myocardial Infarction?en_US
dc.typearticleen_US
dc.relation.journalARQUIVOS BRASILEIROS DE CARDIOLOGIAen_US
dc.contributor.department[Sen, Taner -- Astarcioglu, Mehmet Ali -- Kilit, Celal] Dumlupinar Univ Kutahya, Evliya Celebi Educ & Res Hosp, Kutahya, Turkey -- [Beton, Osman] Sivas Cumhuriyet Univ, Sivas, Turkey -- [Asarcikli, Lale Dinc] Diskapi Educ & Res Hosp, Ankara, Turkeyen_US
dc.contributor.authorIDKilit, Celal -- 0000-0003-3787-0619en_US
dc.identifier.volume108en_US
dc.identifier.issue2en_US
dc.identifier.endpage152en_US
dc.identifier.startpage149en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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