dc.contributor.author | Arihan, Okan | |
dc.contributor.author | Caglayan, Gokhan | |
dc.contributor.author | Bayrak, Sibel | |
dc.contributor.author | Akinci, Aysen | |
dc.contributor.author | Falkmarken, Neslihan Dikmenoglu | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:44:20Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:44:20Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1386-0291 | |
dc.identifier.issn | 1875-8622 | |
dc.identifier.uri | https://dx.doi.org/10.3233/CH-16160 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7026 | |
dc.description | WOS: 000400599300001 | en_US |
dc.description | PubMed ID: 27814281 | en_US |
dc.description.abstract | AIM: To evaluate hemorheological parameters in patients with fibromyalgia syndrome (FMS) in order to elucidate the etiology of the disease. METHODS: Twenty-three adult FMS patients and 20 healthy controls were enrolled in the study. Diabetics, hypertensives and those with any rheumatological disorder or use drugs or smoking cigarette were excluded from the study. Following parameters were analyzed in each subject; erythrocyte deformability, erythrocyte aggregation, plasma viscosity, complete blood count, fasting blood glucose, fibrinogen, albumin, globulin and lipid profile. RESULTS: Erythrocyte elongation indices indicating deformability of erythrocytes were higher in FMS patients (0.564 +/- 0.002 at 16.87mPa and 0.605 +/- 0.002 at 30mPa shear rate) than controls (0.558 +/- 0.001 at 16.87mPa and 0.600 +/- 0.003 at 30mPa shear rate). Erythrocyte aggregation speed was higher in FMS patients (2.1 +/- 0.1 s) than controls (2.3 +/- 0.2 s). Erythrocyte aggregation index was also higher in FMS patients (65.5 +/- 1.3) than controls (62.9 +/- 1.5). Erythrocyte aggregation amplitude and plasma viscosity values were similar in both groups (both p > 0.05). Among the complete blood count and biochemical parameters, only albumin levels were lower in the FM patients than controls (p < 0.05). CONCLUSION: Our results indicate higher erythrocyte deformability and quicker erythrocyte aggregation in FM patients. | en_US |
dc.description.sponsorship | Hacettepe University Scientific Research Administration | en_US |
dc.description.sponsorship | This study was supported by Hacettepe University Scientific Research Administration. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | IOS PRESS | en_US |
dc.relation.isversionof | 10.3233/CH-16160 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Erythrocyte aggregation | en_US |
dc.subject | blood viscosity | en_US |
dc.subject | erythrocyte deformability | en_US |
dc.subject | erythrocyte | en_US |
dc.subject | hemorheology | en_US |
dc.subject | plasma viscosity | en_US |
dc.subject | fibromyalgia | en_US |
dc.title | Hemorheological parameters in patients with fibromyalgia syndrome | en_US |
dc.type | article | en_US |
dc.relation.journal | CLINICAL HEMORHEOLOGY AND MICROCIRCULATION | en_US |
dc.contributor.department | [Arihan, Okan] Yuzuncu Yil Univ, Fac Med, Dept Physiol, Van, Turkey -- [Caglayan, Gokhan] Cumhuriyet Univ, Fac Med, Dept Phys & Rehabil Med, Div Rheumatol, Sivas, Turkey -- [Bayrak, Sibel -- Falkmarken, Neslihan Dikmenoglu] Hacettepe Univ, Fac Med, Dept Physiol, Ankara, Turkey -- [Akinci, Aysen] Hacettepe Univ, Fac Med, Dept Phys & Rehabil Med, Ankara, Turkey | en_US |
dc.identifier.volume | 65 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.endpage | 315 | en_US |
dc.identifier.startpage | 309 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |