| dc.description.abstract | Objective: To investigate the symptoms of lung cancer in Turkey and to evaluate approaches to alleviate these symptoms. Subjects and Methods: This study included 1,245 lung cancer patients from 26 centers in Turkey. Demographic characteristics as well as information regarding the disease and treatments were obtained from medical records and patient interviews. Symptoms were evaluated using the Edmonton Symptom Assessment Scale (ESAS) and were graded on a scale between 0 and 10 points. Data were compared using the. 2, Student t, and Mann-Whitney U tests. Potential predictors of symptoms were analyzed using logistic regression analysis. Results: The most common symptom was tiredness (n = 1,002; 82.1%), followed by dyspnea (n = 845; 69.3%), appetite loss (n = 801; 65.7%), pain (n = 798; 65.4%), drowsiness (n = 742; 60.8%), anxiety (n = 704; 57.7%), depression (n = 623; 51.1%), and nausea (n = 557; 45.5%). Of the 1,245 patients, 590 (48.4%) had difficulty in initiating or maintaining sleep. The symptoms were more severe in stages III and IV. Logistic regression analysis indicated a clear association between demographic characteristics and symptom distress, as well as between symptom distress (except nausea) and well-being. Overall, 804 (65.4%) patients used analgesics, 630 (51.5%) received treatment for dyspnea, 242 (19.8%) used enteral/parenteral nutrition, 132 (10.8%) used appetite stimulants, and 129 (10.6%) used anxiolytics/antidepressants. Of the 799 patients who received analgesics, 173 (21.7%) reported that their symptoms were under control, and also those on other various treatment modalities (dyspnea: 78/627 [12.4%], appetite stimulant: 25/132 [18.9%], and anxiolytics/antidepressants: 25/129 [19.4%]) reported that their symptoms were controlled. Conclusion: In this study, the symptoms progressed and became more severe in the advanced stages of lung cancer, and palliative treatment was insufficient in most of the patients in Turkey. (C) 2016 S. Karger AG, Basel | en_US |
| dc.contributor.department | [Bulbul, Y. -- Ozlu, T. -- Ozcelik, N.] Karadeniz Tech Univ, Sch Med, Dept Chest Dis, Farabi Cd 66, TR-61080 Trabzon, Turkey -- [Gunbatar, H. -- Asker, S.] Yuzuncu Yil Univ, Sch Med, Dept Chest Dis, Van, Turkey -- [Saglam, L. -- Kerget, B.] Ataturk Univ, Sch Med, Dept Chest Dis, Erzurum, Turkey -- [Kilic, T.] Inonu Univ, Sch Med, Dept Chest Dis, Malatya, Turkey -- [Kirkil, G.] Firat Univ, Sch Med, Dept Chest Dis, Elazig, Turkey -- [Baris, S. A. -- Basyigit, I.] Kocaeli Univ, Sch Med, Dept Chest Dis, Kocaeli, Turkey -- [Yavsan, D. M. -- Teke, T.] Necmettin Erbakan Univ, Sch Med, Dept Chest Dis, Konya, Turkey -- [Sen, H. S.] Dicle Univ, Sch Med, Dept Chest Dis, Diyarbakir, Turkey -- [Berk, S.] Cumhuriyet Univ, Sch Med, Dept Chest Dis, Sivas, Turkey -- [Acat, M.] Karabuk Univ, Sch Med, Dept Chest Dis, Karabuk, Turkey -- [Intepe, Y. S.] Bozok Univ, Sch Med, Dept Chest Dis, Yozgat, Turkey -- [Toru, U.] Dumlupinar Univ, Sch Med, Dept Chest Dis, Kutahya, Turkey -- [Ayik, S. O. -- Dalli, A.] Katip Celebi Univ, Sch Med, Dept Chest Dis, Izmir, Turkey -- [Ozkurt, S.] Pamukkale Univ, Sch Med, Dept Chest Dis, Denizli, Turkey -- [Mutlu, L. C.] Namik Kemal Univ, Sch Med, Dept Chest Dis, Tekirdag, Turkey -- [Yasar, Z. A. -- Talay, F.] Abant Izzet Baysal Univ, Sch Med, Dept Chest Dis, Bolu, Turkey -- [Arinc, S. -- Akbay, M. O. -- Oruc, O.] Pulm Dis & Thorac Surg Educ & Res Hosp Sureyyapas, Istanbul, Turkey -- [Ozyurek, B. A. -- Erdogan, Y.] Pulm Dis & Thorac Surg Educ & Res Hosp Ataturk, Ankara, Turkey -- [Bahadir, A.] Pulm Dis & Thorac Surg Educ & Res Hosp Yedikule, Istanbul, Turkey -- [Yilmaz, U. -- Tatar, D. -- Erol, S. -- Erbaycu, A. E.] Pulm Dis & Thorac Surg Educ & Res Hosp Dr Suat Se, Izmir, Turkey -- [Senturk, A. -- Ulas, A.] Educ & Res Hosp Ataturk, Ankara, Turkey -- [Ozcelik, M.] Educ & Res Hosp Kartal, Istanbul, Turkey -- [Cakmak, G.] Educ & Res Hosp Haseki, Istanbul, Turkey -- [Esme, H.] Educ & Res Hosp Konya, Konya, Turkey -- [Yumuk, P. F. -- Besiroglu, M.] Marmara Univ, Dept Med Oncol, Sch Med, Istanbul, Turkey -- [Erol, M. M.] Uludag Univ, Dept Thorac Surg, Sch Med, Bursa, Turkey -- [Can, H.] Katip Celebi Univ, Dept Family Med, Sch Med, Izmir, Turkey | en_US |
