dc.contributor.author | Uslu, Sema | |
dc.contributor.author | Yoruk, Mecit | |
dc.contributor.author | Mis, Leyla | |
dc.contributor.author | Comba, Bahat | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:44:38Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:44:38Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1300-6045 | |
dc.identifier.uri | https://dx.doi.org/10.9775/kvfd.2016.15557 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7127 | |
dc.description | WOS: 000382113800011 | en_US |
dc.description.abstract | The main objective of this study was to investigate the localisation of estrogen receptor alpha (ER-alpha) and progesterone receptor B (PR-B) by immunohistochemistry in goat ovaries during in- and out of breeding season. The ovaries obtained from goats slaughtered in breeding season (n=10) and non-breeding season (n=10) were used. From the same animals, blood samples were taken to determine the levels of serum steroid hormones (E-2, P-4). The ER-alpha and PR-B immunohistochemical distributions within the ovaries were determined by the ABC method. In breeding season, the ER-alpha was detected in the germinal epithelium and follicular granulosa cells. The PR-B was determined to concentrate on the corpus luteum (CL) cells. The same receptors were also found to be weak in the theca externa cells of preovulatory follicles. In non-breeding season, the ER-alpha germinal epithelium and smooth muscle cells of certain blood vessels showed a weak positive reaction. The PR-B was positively stained in the germinal epithelium and few stroma cells. It was suggested that the average steroid hormone profiles in breeding (E-2: 11.83 +/- 1.70 pg/mL, P-4: 10.08 +/- 1.58 ng/ml) and non-breeding season (E-2 2.33 +/- 0.85 pg/ml, P-4 0.21 +/- 0.04 ng/ml) correlated well with the localisation intensity of receptors in goat ovaries. | en_US |
dc.description.sponsorship | Yuzuncu Yil University [2013-VF-B018] | en_US |
dc.description.sponsorship | We greatly acknowledge funding from the Yuzuncu Yil University Scientific Research Projects Directorate for conducting this project (No: 2013-VF-B018). | en_US |
dc.language.iso | eng | en_US |
dc.publisher | KAFKAS UNIV, VETERINER FAKULTESI DERGISI | en_US |
dc.relation.isversionof | 10.9775/kvfd.2016.15557 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Goat | en_US |
dc.subject | ovary | en_US |
dc.subject | immunohistochemistry | en_US |
dc.subject | estrogen receptor a | en_US |
dc.subject | progesterone receptor B | en_US |
dc.title | Localisation of Estrogen Receptor Alpha and Progesterone Receptor B in Goat Ovaries During Breeding and Non-Breeding Season | en_US |
dc.type | article | en_US |
dc.relation.journal | KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI | en_US |
dc.contributor.department | [Uslu, Sema] Cumhuriyet Univ, Fac Vet Med, Dept Histol & Embryol, TR-58140 Sivas, Turkey -- [Yoruk, Mecit] Yuzuncu Yil Univ, Fac Vet Med, Dept Histol & Embryol, TR-65080 Van, Turkey -- [Mis, Leyla -- Comba, Bahat] Yuzuncu Yil Univ, Fac Vet Med, Dept Physiol, TR-65080 Van, Turkey | en_US |
dc.contributor.authorID | COMBA, BAHAT -- 0000-0002-3419-4144 | en_US |
dc.identifier.volume | 22 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.endpage | 882 | en_US |
dc.identifier.startpage | 877 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |