Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer
dc.contributor.author | Tutar, Yusuf | |
dc.contributor.author | Ozgur, Aykut | |
dc.contributor.author | Tutar, Esen | |
dc.contributor.author | Tutar, Lutfi | |
dc.contributor.author | Pulliero, Alessandra | |
dc.contributor.author | Izzotti, Alberto | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:44:43Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:44:43Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 0753-3322 | |
dc.identifier.issn | 1950-6007 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.biopha.2016.08.043 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7154 | |
dc.description | WOS: 000390433400142 | en_US |
dc.description | PubMed ID: 27551766 | en_US |
dc.description.abstract | Lung cancer is one of the most common mortal cancer types both for men and women. Several different biomarkers have been analyzed to reveal lung cancer prognosis pathways for developing efficient therapeutics and diagnostic agents. microRNAs (miRNAs) and pseudogenes are critical biomarkers in lung cancer and alteration of their expression levels has been identified in each step of lung cancer tumorigenesis. miRNAs and pseudogenes are crucial gene regulators in normal cells as well as in lung cancer cells, and they have both oncogenic and tumor-suppressive roles in lung cancer tumorigenesis. In this study, we have determined the relationship between lung cancer related oncogenes and miRNAs along with pseudogenes in lung cancer, and the results indicate their potential as biological markers for diagnostic and therapeutic purposes. (C) 2016 Elsevier Masson SAS. All rights reserved. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER | en_US |
dc.relation.isversionof | 10.1016/j.biopha.2016.08.043 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | miRNA | en_US |
dc.subject | Pseudogene | en_US |
dc.subject | Lung cancer | en_US |
dc.subject | Biomarker | en_US |
dc.subject | miRNA therapeutics | en_US |
dc.title | Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer | en_US |
dc.type | review | en_US |
dc.relation.journal | BIOMEDICINE & PHARMACOTHERAPY | en_US |
dc.contributor.department | [Tutar, Yusuf] Cumhuriyet Univ, Div Biochem, Dept Basic Sci, Fac Pharm, TR-58140 Sivas, Turkey -- [Ozgur, Aykut] Gaziosmanpasa Univ, Fac Nat Sci & Engn, Dept Bioengn, Tokat, Turkey -- [Tutar, Esen] Kahramanmaras Sutcu Imam Univ, Grad Sch Nat & Appl Sci, Dept Bioengn & Sci, Kahramanmaras, Turkey -- [Tutar, Lutfi] Kahramanmaras Sutcu Imam Univ, Fac Sci & Letters, Dept Biol, Kahramanmaras, Turkey -- [Pulliero, Alessandra -- Izzotti, Alberto] Univ Genoa, Dept Hlth Sci, I-16126 Genoa, Italy -- [Izzotti, Alberto] IRCCS Univ Hosp San Martino IST, Natl Inst Canc Res, Mutagenesis Unit, Genoa, Italy | en_US |
dc.identifier.volume | 83 | en_US |
dc.identifier.endpage | 1190 | en_US |
dc.identifier.startpage | 1182 | en_US |
dc.relation.publicationcategory | Diğer | en_US |
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