dc.contributor.author | Ozturk, Sahin | |
dc.contributor.author | Gurdere, Meliha Burcu | |
dc.contributor.author | Gezegen, Hayreddin | |
dc.contributor.author | Ceylan, Mustafa | |
dc.contributor.author | Budak, Yakup | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:44:44Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:44:44Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1307-6175 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7158 | |
dc.description | WOS: 000411597000007 | en_US |
dc.description.abstract | 2-Alkoxy-4-(aryl)-5H-indeno[ 1,2-b] pyridine-3-carbonitriles (3a-e and 4a-e) were synthesized via multicomponent reaction from 2-aryl-methylidineindan-1-ones (1a-e), malononitrile and K2CO3 in ethanol and/or methanol. The structures of obtained compounds (3a-e and 4a-e) were characterized using the spectroscopic methods (NMR, IR) and elemental analysis. Addition, the in vitro antimicrobial activities of compounds (3a-e) were tested against the five human pathogenic bacteria. Penicillin G and Ceftriaxone antibiotics were used as positive control. The results were given as MIC values (minimum inhibition concentration), and compounds 3b-d showed very high activity against Escherichia coli 111. | en_US |
dc.description.sponsorship | Gaziosmanpasa University, Scientific Research Projects Commission [BAP2011/107] | en_US |
dc.description.sponsorship | The authors are indebted to the Gaziosmanpasa University, Scientific Research Projects Commission (Project No: BAP2011/107) for financial supports. We thanks to editor and reviewers due to their recommendations for improve of this article. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | ACG PUBLICATIONS | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | 1-Indanone | en_US |
dc.subject | malononitrile | en_US |
dc.subject | pyridine-3-carbonitrile | en_US |
dc.subject | antimicrobial activity | en_US |
dc.title | Potassium carbonate mediated one-pot synthesis and antimicrobial activities of 2-alkoxy-4-(aryl)-5H-indeno[1,2b] pyridine-3-carbonitriles | en_US |
dc.type | article | en_US |
dc.relation.journal | ORGANIC COMMUNICATIONS | en_US |
dc.contributor.department | [Ozturk, Sahin -- Gurdere, Meliha Burcu -- Ceylan, Mustafa -- Budak, Yakup] Gaziosmanpasa Univ, Fac Arts & Sci, Dept Chem, TR-60250 Tokat, Turkey -- [Gezegen, Hayreddin] Cumhuriyet Univ, Fac Hlth Sci, Dept Nutr & Dietet, Sivas, Turkey | en_US |
dc.contributor.authorID | Gezegen, Hayreddin -- 0000-0003-3602-7400 | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.endpage | 132 | en_US |
dc.identifier.startpage | 125 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |