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dc.contributor.authorDogan, Volkan
dc.contributor.authorBasaran, Ozcan
dc.contributor.authorBeton, Osman
dc.contributor.authorTekinalp, Mehmet
dc.contributor.authorBolat, Ismail
dc.contributor.authorKalaycioglu, Ezgi
dc.contributor.authorAykan, Ahmet Cagri
dc.contributor.authorTasar, Onur
dc.contributor.authorSafak, Ozgen
dc.contributor.authorKalcik, Macit
dc.contributor.authorYaman, Mehmet
dc.contributor.authorKirma, Cevat
dc.contributor.authorBiteker, Murat
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:44:55Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:44:55Z
dc.date.issued2016
dc.identifier.issn0954-6928
dc.identifier.issn1473-5830
dc.identifier.urihttps://dx.doi.org/10.1097/MCA.0000000000000389
dc.identifier.urihttps://hdl.handle.net/20.500.12418/7211
dc.descriptionWOS: 000380806300010en_US
dc.descriptionPubMed ID: 27182772en_US
dc.description.abstractBackground Nonvalvular atrial fibrillation (NVAF) frequently coexists with coronary artery disease (CAD). However, the optimal antithrombotic strategy for patients with concomitant CAD and NVAF is controversial. The aim of this study is to assess the prevalence of CAD with NVAF and to determine antithrombotic treatment options in patients with or without a history of CAD. Methods ReAl-life Multicenter Survey Evaluating Stroke prevention strategies in Turkey (RAMSES study) was a cross-sectional, multicenter, nationwide observational study carried out in NVAF patients. We studied the clinical data of 6264 Turkish patients participating in the RAMSES study. Demographic properties and antithrombotic therapies were recorded and compared between patients with and without CAD. Results CAD was present in 1828 (29.2%) of patients with NVAF. Most of the NVAF patients with CAD were men (58%) and comorbid diseases were significantly more common in patients with CAD. Although patients with CAD had higher CHA(2)DS(2)VASc scores than those without disease (4.1 +/- 1.5 vs. 2.9 +/- 1.5; P=0.001), they had lower use of oral anticoagulant (OAC) therapy (66.1 vs. 74.4%, P=0.01). Among OAC drugs, warfarin was the preferred medication in patients with CAD (35.4 vs. 30.6%, P=0.01), whereas nonvitamin K antagonist oral anticoagulants were preferred in patients without CAD (40 vs. 34.3%, P=0.01). Patients with CAD required nearly three-fold higher antiplatelet treatment compared with patients without CAD (57.8 vs. 21.4%, P<0.001). Conclusion CAD affects nearly one-third of patients with NVAF in a real-world setting. Although they merit more aggressive therapy, patients with CAD and NVAF were less likely to receive OAC therapy. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.en_US
dc.language.isoengen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.isversionof10.1097/MCA.0000000000000389en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectanticoagulant therapyen_US
dc.subjectcoronary artery diseaseen_US
dc.subjectnonvalvular atrial fibrillationen_US
dc.titleCoronary artery disease in outpatients with nonvalvular atrial fibrillation: results from the multicenter RAMSES studyen_US
dc.typearticleen_US
dc.relation.journalCORONARY ARTERY DISEASEen_US
dc.contributor.department[Dogan, Volkan -- Basaran, Ozcan -- Biteker, Murat] Mugla Sitki Kocman Univ, Dept Cardiol, Fac Med, Mugla, Turkey -- [Beton, Osman] Sivas Cumhuriyet Univ, Dept Cardiol, Fac Med, Sivas, Turkey -- [Tekinalp, Mehmet] Kahramanmaras Necip Fazil State Hosp, Dept Cardiol, Kahramanmaras, Turkey -- [Bolat, Ismail] Fethiye State Hosp, Dept Cardiol, Fethiye, Turkey -- [Kalaycioglu, Ezgi -- Aykan, Ahmet Cagri] Trabzon Ahi Evren Chest Cardiovasc Surg Educ & Re, Dept Cardiol, Trabzon, Turkey -- [Tasar, Onur] Elazig Educ & Res Hosp, Dept Cardiol, Elazig, Turkey -- [Safak, Ozgen] Burdur State Hosp, Dept Cardiol, Burdur, Turkey -- [Kalcik, Macit] Iskilip Atif Hoca State Hosp, Dept Cardiol, Iskilip, Turkey -- [Yaman, Mehmet] Samsun Educ & Res Hosp, Dept Cardiol, Samsun, Turkey -- [Kirma, Cevat] Kartal Kosuyolu Heart Educ & Res Hosp, Istanbul, Turkeyen_US
dc.contributor.authorIDBASARAN, OZCAN -- 0000-0002-6384-6455en_US
dc.identifier.volume27en_US
dc.identifier.issue6en_US
dc.identifier.endpage503en_US
dc.identifier.startpage497en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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