dc.contributor.author | Ozdal, Aysegul | |
dc.contributor.author | Erselcan, Taner | |
dc.contributor.author | Ozdemir, Ozturk | |
dc.contributor.author | Silov, Guler | |
dc.contributor.author | Erdogan, Zeynep | |
dc.contributor.author | Turhal, Ozgul | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:45:11Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:45:11Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 0972-3919 | |
dc.identifier.issn | 0974-0244 | |
dc.identifier.uri | https://dx.doi.org/10.4103/0972-3919.183621 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7276 | |
dc.description | WOS: 000379319300005 | en_US |
dc.description | PubMed ID: 27385886 | en_US |
dc.description.abstract | Objective: In the current study, we aimed to explore whether there is alteration between pre-and post-treatment micronucleus (MN) frequencies induced by internal and external ionizing radiation. Materials and Methods: The study enrolled a total of 67 patients including patients admitted to our hospital for treatment of hyperthyroidism (n = 17), scanning with low-dose I-131 (n = 15), and ablative therapy with high-dose I-131 (n = 15) at Department of Nuclear Medicine as well as patients with different diagnoses receiving external radiotherapy with various doses and durations at Department of Radiation Oncology (n = 20). Thirty-two patients who received radioactive iodine and returned for a follow-up visit at 1 month. Results: Considering both pre-and post-treatment MN frequencies of each group, lowest MN frequencies were detected for patients undergoing screening with low-dose I-131, and highest MN frequencies were found in radiotherapy patients. Comparison of pre-and post-treatment MN frequencies among hyperthyroidism, when pre-and post-treatment MN frequencies compared among hyperthyroidism, I-131 whole body scanning, ablation, and radiotherapy patient groups differences between MN frequencies were significant for each group (P < 0.05). Conclusion: Our study showed that MN analysis might be of value in determining chromosome damage that could potentially occur in patients exposed to internal and external radiation. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MEDKNOW PUBLICATIONS & MEDIA PVT LTD | en_US |
dc.relation.isversionof | 10.4103/0972-3919.183621 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Ionizing radiation | en_US |
dc.subject | micronucleus | en_US |
dc.subject | radioiodine | en_US |
dc.title | Micronucleus frequencies in groups receiving external or internal radiation | en_US |
dc.type | article | en_US |
dc.relation.journal | INDIAN JOURNAL OF NUCLEAR MEDICINE | en_US |
dc.contributor.department | [Ozdal, Aysegul -- Silov, Guler -- Erdogan, Zeynep -- Turhal, Ozgul] Kayseri Training & Res Hosp, Dept Nucl Med, TR-38010 Kayseri, Turkey -- [Erselcan, Taner] Cumhuriyet Univ, Dept Nucl Med, Sch Med, TR-58140 Sivas, Turkey -- [Ozdemir, Ozturk] Cumhuriyet Univ, Dept Med Genet, Sch Med, TR-58140 Sivas, Turkey | en_US |
dc.identifier.volume | 31 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.endpage | 184 | en_US |
dc.identifier.startpage | 179 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |