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Now showing items 11-16 of 16
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(Bentham Science Publishers, 2023/12/1)
Background: Fibromyalgia is a soft tissue rheumatism characterized by chronic and widespread musculoskeletal pain at specific points in the body.
Objectives: In this study, we aimed to investigate the relationship between ...
Experimental and theoretical insights about the effect of some newly designed azomethine group-contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 2023/8/5)
We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy-
two-membered macroheterocyclic compounds and the investigation of their activity against the neurob-
lastoma cell line. ...
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 2023/9/28)
We herein report the determination of the cytotoxic activity and expression profiles of
some DNArepair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The
studied novel compounds were ...
Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)
Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ...
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 05.03.2023)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed compound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ...
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 2023/3/5)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed com-
pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In
recent years, ...