dc.contributor.author | Akkar, Ozlem Bozoklu | |
dc.contributor.author | Sancakdar, Enver | |
dc.contributor.author | Karakus, Savas | |
dc.contributor.author | Yildiz, Caglar | |
dc.contributor.author | Akkar, Ismail | |
dc.contributor.author | Arslan, Murat | |
dc.contributor.author | Sahin, Irfan Oguz | |
dc.contributor.author | Yenicesu, Ayse Gonca Imir | |
dc.contributor.author | Cetin, Ali | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:45:39Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:45:39Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1643-3750 | |
dc.identifier.uri | https://dx.doi.org/10.12659/MSM.897983 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7377 | |
dc.description | WOS: 000374178600001 | en_US |
dc.description | PubMed ID: 27072780 | en_US |
dc.description.abstract | Background: The aim of this study was to evaluate the association of maternal serum 25-hydroxyvitamin D, paraoxonase 1, and neutrophil-to-lymphocyte ratio in women having early spontaneous preterm birth without clinical chorioamnionitis. Material/Methods: This study was prospectively administered in women referred to our obstetrics service with preterm labor that resulted in preterm birth (n=35) and term labor that ended in term birth (n=44). The maternal serum levels of 25-hydroxyvitamin D and paraoxonase 1 were measured and neutrophil-to-lymphocyte ratio was calculated. Results: The 25-hydroxyvitamin D and paraoxonase 1 levels of the preterm group were significantly lower than those of the term group (p<0.05). The neutrophil-to-lymphocyte ratio value of the preterm group was significantly higher than that of the term group (p<0.05). There was a significant but small positive correlation between the serum levels of 25-hydroxyvitamin D and paraoxonase 1 in the preterm group (r=0.35; p=0.021). Conclusions: Decreased maternal serum 25-hydroxyvitamin D and paraoxonase 1 levels and increased neutrophil-to-lymphocyte ratio may have a role in the etiology of spontaneous preterm birth. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | INT SCIENTIFIC LITERATURE, INC | en_US |
dc.relation.isversionof | 10.12659/MSM.897983 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | 25-hydroxyvitamin D | en_US |
dc.subject | Neutrophil to Lymphocyte Ratio | en_US |
dc.subject | Paraoxonase 1 | en_US |
dc.subject | Preterm Birth | en_US |
dc.title | Evaluation of Maternal Serum 25-Hydroxyvitamin D, Paraoxonase 1 Levels, and Neutrophil-to-Lymphocyte Ratio in Spontaneous Preterm Birth | en_US |
dc.type | article | en_US |
dc.relation.journal | MEDICAL SCIENCE MONITOR | en_US |
dc.contributor.department | [Akkar, Ozlem Bozoklu -- Karakus, Savas -- Yildiz, Caglar -- Yenicesu, Ayse Gonca Imir -- Cetin, Ali] Cumhuriyet Univ, Dept Obstet & Gynecol, Sivas, Turkey -- [Sancakdar, Enver] Cumhuriyet Univ, Dept Med Biochem, Sivas, Turkey -- [Akkar, Ismail] Sivas State Hosp, Dept Pediat, Sivas, Turkey -- [Arslan, Murat] Sivas State Hosp, Dept Obstet & Gynecol, Sivas, Turkey -- [Sahin, Irfan Oguz] Cumhuriyet Univ, Dept Pediat, Sivas, Turkey | en_US |
dc.contributor.authorID | Cetin, Ali -- 0000-0002-5767-7894 | en_US |
dc.identifier.volume | 22 | en_US |
dc.identifier.endpage | 1243 | en_US |
dc.identifier.startpage | 1238 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |