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dc.contributor.authorAkkar, Ozlem Bozoklu
dc.contributor.authorSancakdar, Enver
dc.contributor.authorKarakus, Savas
dc.contributor.authorYildiz, Caglar
dc.contributor.authorAkkar, Ismail
dc.contributor.authorArslan, Murat
dc.contributor.authorSahin, Irfan Oguz
dc.contributor.authorYenicesu, Ayse Gonca Imir
dc.contributor.authorCetin, Ali
dc.descriptionWOS: 000374178600001en_US
dc.descriptionPubMed ID: 27072780en_US
dc.description.abstractBackground: The aim of this study was to evaluate the association of maternal serum 25-hydroxyvitamin D, paraoxonase 1, and neutrophil-to-lymphocyte ratio in women having early spontaneous preterm birth without clinical chorioamnionitis. Material/Methods: This study was prospectively administered in women referred to our obstetrics service with preterm labor that resulted in preterm birth (n=35) and term labor that ended in term birth (n=44). The maternal serum levels of 25-hydroxyvitamin D and paraoxonase 1 were measured and neutrophil-to-lymphocyte ratio was calculated. Results: The 25-hydroxyvitamin D and paraoxonase 1 levels of the preterm group were significantly lower than those of the term group (p<0.05). The neutrophil-to-lymphocyte ratio value of the preterm group was significantly higher than that of the term group (p<0.05). There was a significant but small positive correlation between the serum levels of 25-hydroxyvitamin D and paraoxonase 1 in the preterm group (r=0.35; p=0.021). Conclusions: Decreased maternal serum 25-hydroxyvitamin D and paraoxonase 1 levels and increased neutrophil-to-lymphocyte ratio may have a role in the etiology of spontaneous preterm birth.en_US
dc.subject25-hydroxyvitamin Den_US
dc.subjectNeutrophil to Lymphocyte Ratioen_US
dc.subjectParaoxonase 1en_US
dc.subjectPreterm Birthen_US
dc.titleEvaluation of Maternal Serum 25-Hydroxyvitamin D, Paraoxonase 1 Levels, and Neutrophil-to-Lymphocyte Ratio in Spontaneous Preterm Birthen_US
dc.relation.journalMEDICAL SCIENCE MONITORen_US
dc.contributor.department[Akkar, Ozlem Bozoklu -- Karakus, Savas -- Yildiz, Caglar -- Yenicesu, Ayse Gonca Imir -- Cetin, Ali] Cumhuriyet Univ, Dept Obstet & Gynecol, Sivas, Turkey -- [Sancakdar, Enver] Cumhuriyet Univ, Dept Med Biochem, Sivas, Turkey -- [Akkar, Ismail] Sivas State Hosp, Dept Pediat, Sivas, Turkey -- [Arslan, Murat] Sivas State Hosp, Dept Obstet & Gynecol, Sivas, Turkey -- [Sahin, Irfan Oguz] Cumhuriyet Univ, Dept Pediat, Sivas, Turkeyen_US
dc.contributor.authorIDCetin, Ali -- 0000-0002-5767-7894en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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