dc.contributor.author | Akgol, G. | |
dc.contributor.author | Yildiz, C. | |
dc.contributor.author | Karakus, S. | |
dc.contributor.author | Koc, M. | |
dc.contributor.author | Dogan, M. | |
dc.contributor.author | Turan, M. | |
dc.contributor.author | Karadayi, K. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:46:23Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:46:23Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 0392-2936 | |
dc.identifier.uri | https://dx.doi.org/10.12892/ejgo3156.2016 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7514 | |
dc.description | WOS: 000388782000005 | en_US |
dc.description | PubMed ID: 29943920 | en_US |
dc.description.abstract | Purpose: Intra-abdominal adhesions are a major complication of healing. Furthermore these adhesions may cause morbidity and sometimes mortality for patients, and also are a financial burden to the health system. Materials and Methods: Cecum abrasion was performed in all rats and solutions containing saline to group 1, 5-fluorouracil to group 2, cisplatin to group 3, paclitaxel to the group 4, and mitomycin-C were administered into the abdomen of the groups, respectively. The intra-abdominal adhesions were scored after the macroscopic evaluation. Results: Among the chemotherapeutic drugs, paclitaxel significantly increases occurring of intra-abdominal adhesions in comparison with the control group and the other drugs according to the evaluation of scoring and statistical studies. Conclusion: It is suggested to use the drugs which have a proven anti-adhesion feature or barriers to the patients who are going to be applied intraperitoneal chemotherapy with paclitaxel. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | I R O G CANADA, INC | en_US |
dc.relation.isversionof | 10.12892/ejgo3156.2016 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Intra-abdominal adhesions | en_US |
dc.subject | Intraperitoneal chemotherapy | en_US |
dc.subject | Cytoreductive surgery | en_US |
dc.title | The effects of intraperitoneal chemotherapeutic agents on adhesion formation | en_US |
dc.type | article | en_US |
dc.relation.journal | EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY | en_US |
dc.contributor.department | [Akgol, G. -- Koc, M. -- Dogan, M. -- Turan, M. -- Karadayi, K.] Cumhuriyet Univ, Sch Med, Dept Gen Surg, TR-58140 Sivas, Turkey -- [Yildiz, C. -- Karakus, S.] Cumhuriyet Univ, Sch Med, Dept Obstet & Gynecol, Sivas, Turkey -- [Karadayi, K.] Cumhuriyet Univ, Sch Med, Div Surg Oncol, Sivas, Turkey | en_US |
dc.identifier.volume | 37 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.endpage | 785 | en_US |
dc.identifier.startpage | 781 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |