Synthesis and in vitro antioxidant evaluation of new bis(-aminoalkyl)phosphinic acid derivatives
Dastan, Sevgi Durna
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Diamines were added to arylaldehydes in ethanol, which resulted in corresponding diimines. Novel bis-1-aminophosphinic acid compounds were synthesized through the interaction of diimines and hypophosphorous acid. The new compounds were characterized by elemental analyses, FT-IR and H-1, C-13 and P-31 NMR techniques. The in vitro antioxidant activity of the newly synthesized compounds were measured and found to exhibit significantly higher antioxidant activity than the standard.