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dc.contributor.authorAkkar, Ozlem Bozoklu
dc.contributor.authorSancakdar, Enver
dc.contributor.authorKarakus, Savas
dc.contributor.authorYildiz, Caglar
dc.contributor.authorArslan, Murat
dc.contributor.authorYucel, Hasan
dc.contributor.authorOzcelik, Fatma
dc.contributor.authorYenicesu, Ayse Gonca Imir
dc.contributor.authorCetin, Meral
dc.contributor.authorCetin, Ali
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:46:40Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:46:40Z
dc.date.issued2016
dc.identifier.issn1940-5901
dc.identifier.urihttps://hdl.handle.net/20.500.12418/7559
dc.descriptionWOS: 000379157300125en_US
dc.description.abstractPreeclampsia is one of the most common causes of maternal and neonatal morbidity and mortality worldwide. We aimed to evaluate the diagnostic values of maternal serum levels of 25-hydroxyvitamin D and paraoxonase 1 (PON1) and neutrophil to lymphocyte ratio (NLR) in the preeclamptic patients and to assess whether they can be used to distinguish the severity of preeclampsia. This prospective study was conducted in women with preeclampsia (n=34) or severe preeclampsia (n=10) and normal pregnancies (n=36), with at least gestational age of 24 weeks. Maternal serum 25-hydroxyvitamin D and PON1 were measured and NLR was calculated. The 25-hydroxyvitamin D levels of the study groups were found comparable (P > 0.05). The normal pregnancy and preeclampsia groups were comparable (P > 0.05) with regard to the PON1 level; however, their PON1 levels were significantly higher compared to the severe preeclampsia group (P < 0.05). The NLRs of the normal pregnancy and preeclampsia groups were found similar (P > 0.05), but the NLR of severe preeclampsia group was significantly higher compared to the normal pregnancy and preeclampsia groups (P < 0.05). The maternal serum 25-hydroxyvitamin D level is not useful as a marker in the diagnosis of preeclampsia; however, the maternal serum PON1 level and NLR may distinguish the patients with preeclampsia with severe features, but not the patients with preeclampsia without severe features.en_US
dc.language.isoengen_US
dc.publisherE-CENTURY PUBLISHING CORPen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject25-hydroxyvitamin Den_US
dc.subjectparaoxonase 1en_US
dc.subjectneutrophil to lymphocyte ratioen_US
dc.subjectpreeclampsiaen_US
dc.subjectsevereen_US
dc.titleComparison of maternal serum vitamin D and paraoxonase 1 levels and neutrophil to lymphocyte ratios of preeclamptic and severe preeclamptic, and normal pregnant womenen_US
dc.typearticleen_US
dc.relation.journalINTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINEen_US
dc.contributor.department[Akkar, Ozlem Bozoklu -- Karakus, Savas -- Yildiz, Caglar -- Yenicesu, Ayse Gonca Imir -- Cetin, Meral -- Cetin, Ali] Cumhuriyet Univ, Fac Med, Dept Obstet & Gynecol, TR-58140 Sivas, Turkey -- [Sancakdar, Enver -- Ozcelik, Fatma] Cumhuriyet Univ, Fac Med, Dept Biochem, TR-58140 Sivas, Turkey -- [Yucel, Hasan] Cumhuriyet Univ, Fac Med, Dept Cardiol, TR-58140 Sivas, Turkey -- [Arslan, Murat] Sivas State Hosp, Dept Obstet & Gynecol, Sivas, Turkeyen_US
dc.contributor.authorIDCetin, Ali -- 0000-0002-5767-7894en_US
dc.identifier.volume9en_US
dc.identifier.issue6en_US
dc.identifier.endpage11816en_US
dc.identifier.startpage11810en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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