dc.contributor.author | Dursan, Feyza | |
dc.contributor.author | Ozec, Ayse Vural | |
dc.contributor.author | Aydin, Huseyin | |
dc.contributor.author | Topalkara, Aysen | |
dc.contributor.author | Darsun, Ayhan | |
dc.contributor.author | Toker, Mustafa Ilker | |
dc.contributor.author | Erdogan, Haydar | |
dc.contributor.author | Arici, Mustafa Kemal | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:47:43Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:47:43Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 2222-3959 | |
dc.identifier.issn | 2227-4898 | |
dc.identifier.uri | https://dx.doi.org/10.3980/j.issn.2222-3959.2015.05.24 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/7713 | |
dc.description | WOS: 000361858600024 | en_US |
dc.description | PubMed ID: 26558214 | en_US |
dc.description.abstract | AIM: To investigate the oxidative stress status of the aqueous humor and serum of patients with pseudoexfoliation (PEX) syndrome and pseudoexfoliative glaucoma (PEG) and to measure paraoxonase (PON) and arylesterase (ARE) levels. METHODS: A total of 78 patients were enrolled in the study, with 26 patients in each separate group. The patients were divided into three groups: the first group entailed PEX syndrome patients, while the second group consisted of patients with PEG and the third group involved patients with no additional systemic diseases, other than the diagnosis of cataract as control. Total oxidative stress (TOS), total antioxidant capacity (TAC), PON, and ARE levels in aqueous humor and serum were measured. RESULTS: TAC, PON and arylesterase levels in aqueous humor and serum of the PEX syndrome and PEG patients were significantly decreased compared with control group (P<0.05). TOS values were higher in patients with PEX syndrome and PEG than controls (P< 0.05). TAC, PON and ARE levels of aqueous humor did not differ significantly between the PEX syndrome and PEG groups CONCLUSION: These findings are potentially of significance and add to the growing body of evidence for oxidative stress in PEX syndrome and PEG. Decreased antioxidant defense and increased oxidative stress system may play an important role in the pathogenesis of PEX syndrome and PEG. | en_US |
dc.description.sponsorship | Turkish Ophthalmology Society | en_US |
dc.description.sponsorship | This study was supported by the Turkish Ophthalmology Society and our study was presented as a poster in the 16th Afro-Asian Congress of Ophthalmology and the 5th Mediterranean Retina Meeting. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | IJO PRESS | en_US |
dc.relation.isversionof | 10.3980/j.issn.2222-3959.2015.05.24 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | pseudoexfoliation syndrome | en_US |
dc.subject | oxidative stress | en_US |
dc.subject | paraoxonase | en_US |
dc.subject | arylesterase | en_US |
dc.title | Total oxidative stress, paraoxonase and arylesterase levels at patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma | en_US |
dc.type | article | en_US |
dc.relation.journal | INTERNATIONAL JOURNAL OF OPHTHALMOLOGY | en_US |
dc.contributor.department | [Dursan, Feyza -- Ozec, Ayse Vural -- Topalkara, Aysen -- Darsun, Ayhan -- Toker, Mustafa Ilker -- Erdogan, Haydar -- Arici, Mustafa Kemal] Cumhuriyet Univ, Sch Med, Dept Ophthalmol, TR-58140 Sivas, Turkey -- [Aydin, Huseyin] Cumhuriyet Univ, Sch Med, Dept Biochem, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | arici, mustafa kemal -- 0000-0002-6350-9723 | en_US |
dc.identifier.volume | 8 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.endpage | 990 | en_US |
dc.identifier.startpage | 985 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |