Influence of preoperative coronary collateral circulation on in-hospital mortality in patients undergoing coronary artery bypass graft surgery with intra-aortic balloon pump support

Abstract

Background Outcomes in patients requiring coronary artery bypass graft (CABG) surgery have been improved with devices such as the intra-aortic balloon pump (IABP). Good coronary collateral circulation (CCC) has been shown to reduce mortality in patients with coronary artery disease (CAD). We aimed to investigate whether poor preoperative CCC grade is a predictor of in-hospital mortality in CABG surgery requiring IABP support. Methods Fifty-five consecutive patients who were undergoing isolated first time on-pump CABG surgery with IABP support were enrolled into this study and CCC of those patients was evaluated. Results Twenty-seven patients had poor CCC and 28 patients had good CCC. In-hospital mortality rate in poor CCC group was significantly higher than good CCC group (14 (50%) vs. 4 (13%), P=0.013). Preoperative hemoglobin level (OR: 0.752; 95% CI, 0.571-0.991, P=0.043), chronic obstructive pulmonary disease (OR: 6.731; 95% CI, 1.159-39.085, P=0.034) and poor CCC grade (OR: 5.750; 95% CI, 1.575-20.986, P=0.008) were associated with post-CABG in-hospital mortality. Poor CCC grade (OR: 4.853; 95% CI, 1.124-20.952, P=0.034) and preoperative hemoglobin level (OR: 0.624; 95% CI, 0.476-0.954, P=0.026) were independent predictors of in-hospital mortality after CABG. Conclusion Preoperative poor CCC and hemoglobin are predictors of in-hospital mortality after CABG with IABP support.