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dc.contributor.authorYildiz, G.
dc.contributor.authorAydin, H.
dc.contributor.authorMagden, K.
dc.contributor.authorYilmaz, A.
dc.contributor.authorHur, E.
dc.contributor.authorCandan, F.
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:57:34Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:57:34Z
dc.date.issued2014
dc.identifier.issn0026-4806
dc.identifier.issn1827-1669
dc.identifier.urihttps://hdl.handle.net/20.500.12418/8330
dc.descriptionWOS: 000333658800008en_US
dc.descriptionPubMed ID: 24572453en_US
dc.description.abstractAim. Chronic kidney disease(CKD) and hemodialysis (HD) are associated with increased oxidative stress. Cardiovascular diseases (CVD) are the most important cause of mortality in these patients. Increased cardiovascular risk is associated with oxidative stress. The aim of this study was to evaluate whether the duration of single session hemodialysis may affect oxidative stress parameters on the patients with end-stage renal disease (ESRD). Methods. Total oxidant status (TOS) and oxidative stress index (OSI) as oxidative markers and total antioxidant status (TAOS), paraoxonase1 (PON1) and arylesterase (ARES) as antioxidant markers were compared hemodialysis therapy before and after the treatment. Results. TOS levels before hemodialysis were found as 4.4 +/- 2.4 mu mol H2O2 Equiv/L, TAOS 2.1 +/- 0.3 mu mol trolox Equiv./L, OSI 0.2 +/- 0.1%, PON1 levels 58.5 +/- 35.6 U/L and ARES levels 22 0.2 U/L while after the HD the respective values were 1.4 +/- 1.2 mu mol H2O2 Equiv/L, 1.4 +/- 0.5 mu mol trolox Equiv./L, 0.1 +/- 0.1%, 54.3 +/- 31.3 U/L, 21.8 +/- 0.1 U/L. A significant decreasing was observed in TOS TAOS OSI and ARES values before the HD compared to after the HD (P=0.0001, P=0.0001, P=0.0001, P=0.031, respectively). Conclusion. This study shows oxidant (TOS, OR) and antioxidant (TAOS, ARES) markers were found to be significantly decrease after the HD compared to pre-hemodialysis. Although reverse is expected it is found that oxidants (indirectly ROS) did not increase and antioxidant reserve decreased in HD.en_US
dc.language.isoengen_US
dc.publisherEDIZIONI MINERVA MEDICAen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArylesteraseen_US
dc.subjectOxidative stressen_US
dc.subjectHemodialysisen_US
dc.titleInfluence of single hemodialysis session on serum paraoxonase-1, arylesterase activity, total oxidant status and total antioxidant statusen_US
dc.typearticleen_US
dc.relation.journalMINERVA MEDICAen_US
dc.contributor.department[Yildiz, G.] Ataturk State Hosp, Zonguldak, Turkey -- [Aydin, H. -- Candan, F.] Cumhuriyet Univ, Sch Med, Sivas, Turkey -- [Magden, K. -- Hur, E.] Bulent Ecevit Univ, Sch Med, Zonguldak, Turkey -- [Yilmaz, A.] Gaziosmanpasa Univ, Sch Med, Tokat, Turkeyen_US
dc.identifier.volume105en_US
dc.identifier.issue1en_US
dc.identifier.endpage87en_US
dc.identifier.startpage79en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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