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dc.contributor.authorKarabay, Oguz
dc.contributor.authorBatirel, Ayse
dc.contributor.authorBalkan, Ilker Inanc
dc.contributor.authorAgalar, Canan
dc.contributor.authorAkalin, Serife
dc.contributor.authorAlici, Ozlem
dc.contributor.authorAlp, Emine
dc.contributor.authorAlta, F. Aybala
dc.contributor.authorAltin, N.
dc.contributor.authorArslan, Ferhat
dc.contributor.authorAslan, Turan
dc.contributor.authorBekiroglu, Nural
dc.contributor.authorCesur, Salim
dc.contributor.authorCelik, Aygul Dogan
dc.contributor.authorDogan, Mustafa
dc.contributor.authorDurdu, Bulent
dc.contributor.authorDuygu, Fazilet
dc.contributor.authorEngin, Aynur
dc.contributor.authorEngin, Derya Ozturk
dc.contributor.authorGonen, Ibak
dc.contributor.authorGuclui, Ertugrul
dc.contributor.authorGuven, Tumer
dc.contributor.authorHatipoglu, Cigdem Ataman
dc.contributor.authorHosoglu, Salih
dc.contributor.authorKarahocagil, Mustafa
dc.contributor.authorKilic, Aysegul Ulu
dc.contributor.authorOrmen, Bahar
dc.contributor.authorOzdemir, Davut
dc.contributor.authorOzer, Serdal
dc.contributor.authorOztoprak, Nefise
dc.contributor.authorSezak, Nurbanu
dc.contributor.authorTurhan, Vedat
dc.contributor.authorTurker, N.
dc.contributor.authorYilmaz, Hava
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:57:40Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:57:40Z
dc.date.issued2014
dc.identifier.issn0393-6384
dc.identifier.urihttps://hdl.handle.net/20.500.12418/8351
dc.descriptionWOS: 000364114800027en_US
dc.description.abstractObjective: This retrospective study aimed to investigate the efficacies of colistin and non-colistin monotherapies in multi-drug resistant Acinetobacter baumannii bacteremia (MDR-AB). Materials and methods: Cases with MDR-AB from 27 tertiary-referral hospitals between January 2009 and December 2012 were included. Patients' data that were on either colistin monotherapy (CM) or non-colistin monotherapy (NCM) were compared. Mortality on Day 14 was the primary endpoint, whereas microbiological eradication and clinical outcome were the secondary ones. Results: Eighty-four cases were included in the study with 36 being in the CM group and 48 in the NCM group. Thirty-eight (452%) cases were male and the mean age was 602 years. The mean durations of pre-MDR-AB hospital stay and intensive care unit stay were 25.8 days and 20.9 days, respectively. All of the cases had fever (>38 degrees C). The mean Pitt bacteremia score (PBS) of the patients was calculated as 6.8, APACHE 2 score as 18.9 and the Charlson co-morbidity index (CCI) as 3.7 (CM: 3.6 vs. NCM: 3.9). Twenty (55.6%) cases in the CM group and 26 cases in the NCM group (542%) (p=0.81) died; 9 cases in the CM group (25%) and 16 cases in the NCM group (33 3%) had treatment failure (P=0.55). Bacteriological eradication was achieved in 20 (55.6%) cases in the CM group and in 36 cases (75%) in the NCM group (P=0.061). Conclusions: No significant difference could be identified between the colistin monotherapy and non-colistin monotherapy options in MDR-AB cases with respect to the results of efficacy and 14-day mortality.en_US
dc.language.isoengen_US
dc.publisherCARBONE EDITOREen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcinetobacter baumanniien_US
dc.subjectbacteremiaen_US
dc.subjectcolistinen_US
dc.subjectmonotherapyen_US
dc.subjectmulti-drug resistanten_US
dc.subjectsepsisen_US
dc.titleEFFICACY OF COLISTIN AND NON-COLISTIN MONOTHERAPIES IN MULTI-DRUG RESISTANT ACINETOBACTER BAUMANNII BACTEREMIA/SEPSISen_US
dc.typearticleen_US
dc.relation.journalACTA MEDICA MEDITERRANEAen_US
dc.contributor.department[Karabay, Oguz] Sakarya Univ, Hlth Sci Inst, Infect Dis & Clin Microbiol, TR-54000 Sakarya, Turkey -- [Batirel, Ayse] Kartal Dr Lutfi Kirdar Educ & Res Hosp, Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Balkan, Ilker Inanc -- Ozer, Serdal] Istanbul Univ, Cerrahpasa Med Fac, Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Agalar, Canan -- Alici, Ozlem] Fatih Sultan Mehmet Educ & Res Hosp, Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Akalin, Serife] Pamukkale Univ, Fac Med, Infect Dis & Clin Microbiol, Denizli, Turkey -- [Alp, Emine -- Kilic, Aysegul Ulu] Erciyes Univ, Fac Med, Infect Dis & Clin Microbiol, Kayseri, Turkey -- [Alta, F. Aybala] Diskapi Educ & Res Hosp, Infect Dis & Clin Microbiol, Ankara, Turkey -- [Altin, N. -- Cesur, Salim] Ankara Etlik Educ & Res Hosp, Infect Dis & Clin Microbiol, Ankara, Turkey -- [Arslan, Ferhat] Istanbul Medipol Univ, Fac Med, Infect Dis, Istanbul, Turkey -- [Aslan, Turan] Bezmi Alem Univ, Fac Med, Infect Dis, Istanbul, Turkey -- [Bekiroglu, Nural] Marmara Univ, Fac Med, Biostat, Istanbul, Turkey -- [Celik, Aygul Dogan] Trakya Univ, Fac Med, Infect Dis, Edirne, Turkey -- [Dogan, Mustafa] Namik Kemal Univ, Fac Med, Infect Dis & Clin Microbiol, Tekirdag, Turkey -- [Durdu, Bulent] Bakirkoy Sadi Konuk Educ & Res Hosp, Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Duygu, Fazilet] Gaziosmanpasa Univ, Fac Med, Infect Dis & Clin Microbiol, Tokat, Turkey -- [Engin, Aynur] Cumhuriyet Univ, Fac Med, Infect Dis & Clin Microbiol, Sivas, Turkey -- [Engin, Derya Ozturk] Haydarpasa Numune Educ & Res Hosp, Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Gonen, Ibak] Suleyman Demirel Univ, Fac Med, Infect Dis & Clin Microbiol, TR-32200 Isparta, Turkey -- [Guven, Tumer] Ankara Ataturk Educ & Res Hosp, Infect Dis & Clin Microbiol, Ankara, Turkey -- [Hatipoglu, Cigdem Ataman] Ankara Educ & Res Hosp, Infect Dis & Clin Microbiol, Ankara, Turkey -- [Hosoglu, Salih] Dicle Univ, Fac Med, Infect Dis & Clin Microbiol, Diyarbakir, Turkey -- [Karahocagil, Mustafa] Yuzuncu Yil Univ, Fac Med, Infect Dis & Clin Microbiol, Van, Turkey -- [Ormen, Bahar] Izmir Ataturk Educ & Res Hosp, Infect Dis & Clin Microbiol, Izmir, Turkey -- [Ozdemir, Davut -- Sezak, Nurbanu -- Turker, N.] Duzce Univ, Educ & Res Hosp, Infect Dis & Clin Microbiol, Duzce, Turkey -- [Oztoprak, Nefise] Antalya Educ & Res Hosp, Infect Dis & Clin Microbiol, Antalya, Turkey -- [Turhan, Vedat] GATA Haydarpasa Educ & Res Hosp, Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Yilmaz, Hava] Ondokuz Mayis Univ, Fac Med, Infect Dis & Clin Microbiol, Samsun, Turkeyen_US
dc.contributor.authorIDKarabay, Oguz -- 0000-0003-0502-432Xen_US
dc.identifier.volume30en_US
dc.identifier.issue5en_US
dc.identifier.endpage1143en_US
dc.identifier.startpage1137en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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