dc.contributor.author | Kirboga, Kadir | |
dc.contributor.author | Ozec, Ayse V. | |
dc.contributor.author | Kosker, Mustafa | |
dc.contributor.author | Dursun, Ayhan | |
dc.contributor.author | Toker, Mustafa I. | |
dc.contributor.author | Aydin, Huseyin | |
dc.contributor.author | Erdogan, Haydar | |
dc.contributor.author | Topalkara, Aysen | |
dc.contributor.author | Arici, Mustafa K. | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:57:43Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:57:43Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 2090-004X | |
dc.identifier.issn | 2090-0058 | |
dc.identifier.uri | https://dx.doi.org/10.1155/2014/820853 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/8362 | |
dc.description | WOS: 000347315600001 | en_US |
dc.description | PubMed ID: 25580282 | en_US |
dc.description.abstract | Purpose. To investigate the oxidant and antioxidant status of patients with type 2 diabetes mellitus and nonproliferative diabetic retinopathy (DRP). Methods. Forty-four patients who had cataract surgery were enrolled in the study. We included 22 patients with DRP in one group and 22 patients in the control group. Samples of aqueous humor and serum were taken from all patients. Serum and aqueous ischemia-modified albumin (IMA), total thiol, total antioxidant capacity (TAC), and total oxidative stress (TOS) levels were compared in two groups. Results. Median serum IMA levels were 44.80 absorbance units in the DRP group and 40.15 absorbance units in the control group (P = 0.031). Median serum total thiol levels in the DRP group were significantly less than those in the control group (3051.13 and 3910.12, resp., P = 0.004). Mean TOS levels in the serum were 2.93 +/- 0.19 in the DRP group and 2.61 +/- 0.26 in the control group (P = 0.039). The differences in mean total thiol, TAC, and TOS levels in the aqueous humor and mean TAC levels in the serum were not statistically significant. Conclusion. IMA, total thiol, and TOS levels in the serum might be useful markers in monitoring the risk of DRP development. | en_US |
dc.description.sponsorship | Ankara Branch of the Turkish Ophthalmology Society | en_US |
dc.description.sponsorship | The authors were funded by Ankara Branch of the Turkish Ophthalmology Society. The sponsor or funding organization had no role in the design or conduct of this research. No conflicting relationship exists for any author. The authors also would like to acknowledge Emire Bor MSc's contributions to the statistical analysis and interpretation of the data. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | HINDAWI PUBLISHING CORPORATION | en_US |
dc.relation.isversionof | 10.1155/2014/820853 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | The Association between Diabetic Retinopathy and Levels of Ischemia-Modified Albumin, Total Thiol, Total Antioxidant Capacity, and Total Oxidative Stress in Serum and Aqueous Humor | en_US |
dc.type | article | en_US |
dc.relation.journal | JOURNAL OF OPHTHALMOLOGY | en_US |
dc.contributor.department | [Kirboga, Kadir -- Ozec, Ayse V. -- Dursun, Ayhan -- Toker, Mustafa I. -- Erdogan, Haydar -- Topalkara, Aysen -- Arici, Mustafa K.] Cumhuriyet Univ, Sch Med, Dept Ophthalmol, TR-58140 Sivas, Turkey -- [Kosker, Mustafa] Ulus State Hosp, Dept Ophthalmol, Ankara, Turkey -- [Aydin, Huseyin] Cumhuriyet Univ, Sch Med, Dept Biochem, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | arici, mustafa kemal -- 0000-0002-6350-9723 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |