dc.contributor.author | Guven, Ahmet Sami | |
dc.contributor.author | Sancakdar, Enver | |
dc.contributor.author | Kaya, Ali | |
dc.contributor.author | Uysal, Elif Bilge | |
dc.contributor.author | Oflaz, Mehmet Burhan | |
dc.contributor.author | Bolat, Fatih | |
dc.contributor.author | Karapinar, Hekim | |
dc.contributor.author | Koc, Elif | |
dc.contributor.author | Icagasioglu, Fusun Dilara | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:58:04Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:58:04Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 1940-5901 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/8431 | |
dc.description | WOS: 000333151800012 | en_US |
dc.description | PubMed ID: 24600498 | en_US |
dc.description.abstract | Purpose: The aim of this study was to assess the role of ABO blood groups in predicting disease severity and bleeding potential in children with Crimean-Congo hemorrhagic fever (CCHF). Methods: One hundred fifty-one hospitalized patients with CCHF were enrolled in this retrospective study. The patients were divided according to O- and non-O-(A, B and AB) blood groups (n=91 and n=60, respectively). They were also classified into two groups (severe and non-severe) based on disease severity (n=29 and n=122, respectively). Demographic characteristics, clinical findings, and hematologic and biochemical parameters of all patients were recorded on admission and discharge. Results: Although, in all cases, compared to the non-O blood group, the ratio of the blood group O was considerably higher (60% vs. 40%) and similarly so in severe cases (58.6% vs. 41.4%), this difference was not statistically significant (p>0.05). The aPTT at discharge and fever duration of the O-blood group were significantly higher than those of the non-O-blood group (p=0.042, p=0.034, respectively). The factor VIII level of the O-blood group was significantly lower than that of the non-O-blood group (p=0.040). Although the ratios of bleeding and severity were higher in the O-blood group compared to the other group, statistical significance was not reached (p>0.05). Conclusions: Consideration of the ABO blood group is important during diagnostic follow-up to assess the severity of CCHF. In clinical practice, pediatric CCHF patients with the O blood group need to be followed closely for tendency to bleed. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | E-CENTURY PUBLISHING CORP | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | CCHF | en_US |
dc.subject | children | en_US |
dc.subject | disease severity | en_US |
dc.subject | bleeding | en_US |
dc.subject | blood groups | en_US |
dc.title | Value of ABO blood group in predicting the severity of children with Crimean-Congo hemorrhagic fever | en_US |
dc.type | article | en_US |
dc.relation.journal | INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | en_US |
dc.contributor.department | [Guven, Ahmet Sami -- Kaya, Ali -- Oflaz, Mehmet Burhan -- Bolat, Fatih -- Koc, Elif -- Icagasioglu, Fusun Dilara] Cumhuriyet Univ, Fac Med, Dept Pediat, TR-58140 Sivas, Turkey -- [Sancakdar, Enver] Cumhuriyet Univ, Fac Med, Dept Biochem, TR-58140 Sivas, Turkey -- [Uysal, Elif Bilge] Cumhuriyet Univ, Fac Med, Dept Microbiol, TR-58140 Sivas, Turkey -- [Karapinar, Hekim] Cumhuriyet Univ, Fac Med, Dept Cardiol, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | Oflaz, Mehmet Burhan -- 0000-0003-1515-4654 | en_US |
dc.identifier.volume | 7 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.endpage | 420 | en_US |
dc.identifier.startpage | 416 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |