dc.contributor.author | Seker, Mehmet Metin | |
dc.contributor.author | Kos, Tugba | |
dc.contributor.author | Ozdemir, Nuriye | |
dc.contributor.author | Seker, Ayse | |
dc.contributor.author | Aksoy, Sercan | |
dc.contributor.author | Uncu, Dogan | |
dc.contributor.author | Zengin, Nurullah | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:58:05Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:58:05Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 1513-7368 | |
dc.identifier.uri | https://dx.doi.org/10.7314/APJCP.2014.15.1.327 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/8433 | |
dc.description | WOS: 000332001000055 | en_US |
dc.description | PubMed ID: 24528050 | en_US |
dc.description.abstract | Background: Ewing sarcoma is a small round cell tumor arising from soft tissue and bone that predominantly affects children and adolescents. The most unfavorable prognostic factor is the presence of distant metastasis at the time of diagnosis. Materials and Methods: The records of 26 Ewing sarcoma patients (14 male, 12 female) were re-evaluated retrospectively. Results: The median age was 26.5 (19-42) years. Eight patients (31%) showed a primary tumor in their extremities, 8 (31%) in the thorax, 4 (15%) at the vertebra, 4 (15%) in the head and neck, and 2 (8%) in the abdomen. Five patients (19%) had distant metastasis at diagnosis. The median progression-free survival was 72 months and 10 months in localized and metastatic disease, respectively (p=0.005). The overall survival rate was 19 months in metastatic disease, and the 5-year overall survival rate was 64% in localized disease (p=0.006). Patients who had localized disease in the extremities and were under age 30 had a favorable prognosis. Conclusions: Although Ewing sarcoma is a tumor affecting children and adolescents, it may be seen in adults, where the prognosis is generally worse. Although it is a highly malignant tumor, it is possible to achieve improved survival with combined modality treatments. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | ASIAN PACIFIC ORGANIZATION CANCER PREVENTION | en_US |
dc.relation.isversionof | 10.7314/APJCP.2014.15.1.327 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Adult cases | en_US |
dc.subject | Ewing sarcoma | en_US |
dc.subject | prognosis | en_US |
dc.subject | Turkey | en_US |
dc.title | Treatment and Outcomes of Ewing Sarcoma in Turkish Adults: A Single Centre Experience | en_US |
dc.type | article | en_US |
dc.relation.journal | ASIAN PACIFIC JOURNAL OF CANCER PREVENTION | en_US |
dc.contributor.department | [Seker, Mehmet Metin] Cumhuriyet Univ, Fac Med, Dept Med Oncol, Sivas, Turkey -- [Kos, Tugba] Manisa State Hosp, Manisa, Turkey -- [Ozdemir, Nuriye -- Uncu, Dogan -- Zengin, Nurullah] Mutki State Hosp, Bitlis, Turkey -- [Seker, Ayse] Numune Educ & Res Hosp, Ankara, Turkey -- [Aksoy, Sercan] Hacettepe Univ, Inst Canc, Ankara, Turkey | en_US |
dc.contributor.authorID | Aksoy, Sercan -- 0000-0003-4984-1049 | en_US |
dc.identifier.volume | 15 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.endpage | 330 | en_US |
dc.identifier.startpage | 327 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |