dc.contributor.author | Tunali, Mustafa | |
dc.contributor.author | Ozdemir, Hakan | |
dc.contributor.author | Kucukodaci, Zafer | |
dc.contributor.author | Akman, Serhan | |
dc.contributor.author | Yaprak, Emre | |
dc.contributor.author | Toker, Hulya | |
dc.contributor.author | Firatli, Erhan | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T09:58:08Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T09:58:08Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 2314-6133 | |
dc.identifier.issn | 2314-6141 | |
dc.identifier.uri | https://dx.doi.org/10.1155/2014/209548 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/8441 | |
dc.description | WOS: 000330672200001 | en_US |
dc.description | PubMed ID: 24563860 | en_US |
dc.description.abstract | We developed a new product called titanium-prepared platelet-rich fibrin (T-PRF). The T-PRF method is based on the hypothesis that titanium may be more effective in activating platelets than the silica activators used with glass tubes in Chouckroun's leukocyte- and platelet-rich fibrin (L-PRF) method. In this study, we aimed to define the structural characteristics of T-PRF and compare it with L-PRF. Blood samples were collected from 10 healthy male volunteers. The blood samples were drawn using a syringe. Nine milliliters was transferred to a dry glass tube, and 9 mL was transferred to a titanium tube. Half of each clot (i.e., the blood that was clotted using T-PRF or L-PRF) was processed with a scanning electron microscope (SEM). The other half of each clot was processed for fluorescence microscopy analysis and light microscopy analysis. The T-PRF samples seemed to have a highly organized network with continuous integrity compared to the other L-PRF samples. Histomorphometric analysis showed that T-PRF fibrin network covers larger area than L-PRF fibrin network; also fibrin seemed thicker in the T-PRF samples. This is the first human study to define T-PRF as an autogenous leukocyte-and platelet-rich fibrin product. The platelet activation by titanium seems to offer some high characteristics to T-PRF. | en_US |
dc.description.sponsorship | Scientific Research Project Coordination Center of the Gulhane Military Medical Academy | en_US |
dc.description.sponsorship | The authors affirm that they have no financial affiliation (e.g., employment, direct payment, stock holdings, retainers, consultantships, patent licensing arrangements, or honoraria) or involvement with any commercial organization with direct financial interest in the subject or materials discussed in this paper, nor have any such arrangements existed in the past three years. Any other potential conflict of interests is disclosed. This study was supported by the Scientific Research Project Coordination Center of the Gulhane Military Medical Academy. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | HINDAWI LTD | en_US |
dc.relation.isversionof | 10.1155/2014/209548 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | A Novel Platelet Concentrate: Titanium-Prepared Platelet-Rich Fibrin | en_US |
dc.type | article | en_US |
dc.relation.journal | BIOMED RESEARCH INTERNATIONAL | en_US |
dc.contributor.department | [Tunali, Mustafa] Gulhane Mil Med Acad, Haydarpasa Training Hosp, Dept Periodontol, TR-34618 Istanbul, Turkey -- [Ozdemir, Hakan -- Toker, Hulya] Cumhuriyet Univ, Sch Dent, Dept Periodontol, TR-58140 Sivas, Turkey -- [Kucukodaci, Zafer] Gulhane Mil Med Acad, Dept Med Pathol, TR-34618 Istanbul, Turkey -- [Akman, Serhan] Selcuk Univ, Sch Dent, Dept Prosthodont, TR-42250 Konya, Turkey -- [Yaprak, Emre] Kocaeli Univ, Sch Dent, Dept Periodontol, TR-41380 Izmit, Turkey -- [Firatli, Erhan] Istanbul Univ, Sch Dent, Dept Periodontol, TR-34303 Istanbul, Turkey | en_US |
dc.contributor.authorID | FIRATLI, Erhan -- 0000-0002-4154-6929; Yaprak, Emre -- 0000-0001-7797-9796 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |