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dc.contributor.authorSafak, Sahin
dc.contributor.authorUslu, Ali Ugur
dc.contributor.authorSerdal, Korkmaz
dc.contributor.authorTurker, Tasliyurt
dc.contributor.authorSoner, Senel
dc.contributor.authorLutfi, Akyol
dc.descriptionWOS: 000349632900021en_US
dc.descriptionPubMed ID: 25834502en_US
dc.description.abstractBackground: Systemic lupus erythematosus (SLE) may be characterized by periods of remissions and chronic or acute relapses. The complexity of clinical presentation of the SLE patients leads to incorrect evaluation of disease activity. Mean platelet volume (MPV) has been studied as a simple inflammatory marker in several diseases. There is no study in the literature about MPV levels in adult SLE patients with arthritis. Objectives: We aimed to investigate the MPV levels in the SLE population with arthritis during and between activations. Methods: The study consisted of 44 SLE patients with arthritis in activation period (Group 1), the same 44 SLE patients with arthritis in remission period (Group 2) and 44 healthy controls (Group 3). Erythrocyte sedimentation rate (ESR), creactive protein (CRP), white blood cell count, platelet count, and mean platelet volume (MPV) levels were retrospectively recorded from patient files. Results: The mean ages of the SLE subjects were 42 +/- 16 years, while the mean ages of controls was 41 coproduct 17 years. MPV was significantly lower in Group 1(7.66 +/- 0.89fL) than in Group 2 (8.61 +/- 1.06 fL) and Group 3(8.62 +/- 1.11fL) (p<0.0001). The differences between groups reached statistical significance. Conclusions: We suggest that MPV levels decrease in patients with arthritis of SLE activation when compared to the same patients in remission and healthy controls.en_US
dc.subjectSystemic lupus erythematosusen_US
dc.subjectMean platelet volumeen_US
dc.titleAssociation between mean platelet volume levels and inflammation in SLE patients presented with arthritisen_US
dc.relation.journalAFRICAN HEALTH SCIENCESen_US
dc.contributor.department[Safak, Sahin -- Turker, Tasliyurt] Gaziosmanpasa Univ, Fac Med, Dept Internal Med, Tokat, Turkey -- [Uslu, Ali Ugur -- Serdal, Korkmaz] Cumhuriyet Univ, Fac Med, Dept Internal Med, Sivas, Turkey -- [Soner, Senel] Erciyes Univ, Fac Med, Dept Rheumatol, Kayseri, Turkey -- [Lutfi, Akyol] Bozok Univ, Fac Med, Dept Internal Med, Yozgat, Turkeyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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