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Investigation of acute effects of aflatoxin on rat proximal and distal colon spontaneous contractions
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Aflatoxins are one of the most potent toxic, mutagenic, teratogenic, cancerogenic, and immunosuppresive substances that naturally Occurring contaminants of food. There are some studies in various animal species that have ...
Comparison of In Vitro Effects of Opioid Analgesics on Spontaneous Proximal and Distal Colon Contractions in Healthy Rats and Rats with Peritonitis
(AVES, 2018)
Objective: The goal of this study was to investigate and compare the effects of opioids on proximal and distal colon contractions in normal rats and rats with peritonitis, with and without the presence of naloxone in the ...
Effects of formoterol and BRL 37344 on human umbilical arteries in vitro in normotensive and pre-eclamptic pregnancy
(ELSEVIER SCIENCE INC, 2007)
Alterations in vascular responses to beta-adrenoceptor agonists in normotensive pregnancy and pre-eclampsia are not fully understood. Thus, we studied changes in vasodilator responses to beta(2)-adrenoceptor agonist ...
Investigation of the role of the NO-cGMP pathway on YC-1 and DEA/NO effects on thoracic aorta smooth muscle responses in a rat preeclampsia model
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2013)
The present study was designed to investigate the effects of YC-1, a nitric oxide (NO)-independent soluble guanylate cyclase (sGC) activator, and DEA/NO, a NO donor, on smooth muscle responses in the preeclampsia model ...
Rho-kinase inhibitors Y-27632 and fasudil prevent agonist-induced vasospasm in human radial artery
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2009)
Radial artery (RA) vasospasm remains a potential cause of early graft failure after coronary artery bypass graft surgery, despite pretreatment with alpha-adrenergic or calcium channel blockers. Our aim was to investigate ...
Do antibiotics contribute to postoperative ileus? Contractile responses of ileum smooth muscle in guinea pigs to long-term parenteral ceftriaxone and ampicillin
(BLACKWELL PUBLISHING, 2006)
Background: Antibiotics may impair small bowel smooth muscle contractility and contribute to postoperative ileus. The aim of this study was to compare the contractile responses of ileum smooth muscle to different agonists ...
Effects of NO/L-Arginine Pathway on Gallbladder Contractility in Bile Duct Ligated Guinea Pigs
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009)
Background. Common bile duct ligation (CBDL) produces gallbladder distension and acute inflammation similar to that seen in human acute acalculous cholecystitis. CBDL in the guinea pig affects smooth muscle contractility. ...
The effects of endocannabinoid receptor agonist anandamide and antagonist rimonabant on opioid analgesia and tolerance in rats
(GENERAL PHYSIOL AND BIOPHYSICS, 2015)
The role of the cannabinoid (CB) system in the tolerance to analgesic effect of opioid remains obscure. The aim of the present study was to evaluate the effects of the endocannabinoid nonselective receptor agonist anandamide ...
Investigation of the vasorelaxant effects of 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) and diethylamine/nitric oxide (DEA/NO) on the human radial artery used as coronary bypass graft
(NATL RESEARCH COUNCIL CANADA-N R C RESEARCH PRESS, 2007)
The radial artery (RA) is used as a spastic coronary bypass graft. This study was designed to investigate the mechanism of vasorelaxant effects of YC-1 (3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole), a nitric oxide ...
Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits
(BLACKWELL PUBLISHING, 2006)
Introduction. The incidence of hormonal dysfunction as a cause of impotence remains controversial. However, several recent studies have reported evidence of hormonal abnormalities in 25-35% of impotent men. Hypothyroidism ...