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Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure
(BMC, 2016)
Substantial attention and resources have been directed to improving outcomes of patients with critical illnesses, in particular sepsis, but all recent clinical trials testing various interventions or strategies have failed ...
Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper
(ELSEVIER IRELAND LTD, 2016)
Levosimendan is a positive inotrope with vasodilating properties (inodilator) indicated for decompensated heart failure (HF) patients with low cardiac output. Accumulated evidence supports several pleiotropic effects of ...
The performance and analysis of the thermoelectric generator system used in diesel engines
(PERGAMON-ELSEVIER SCIENCE LTD, 2016)
Thermoelectric generator (TEG) has drawn significant for the waste heat recovery systems. In this study, a prototype has been developed for the working principle suitable to the thermoelectric generator systems. The exhaust ...
Acute heart failure and cardiogenic shock: a multidisciplinary practical guidance
(SPRINGER, 2016)
Purpose: Acute heart failure (AHF) causes high burden of mortality, morbidity, and repeated hospitalizations worldwide. This guidance paper describes the tailored treatment approaches of different clinical scenarios of AHF ...
Biosafety standards for working with Crimean-Congo hemorrhagic fever virus
(MICROBIOLOGY SOC, 2016)
In countries from which Crimean-Congo haemorrhagic fever (CCHF) is absent, the causative virus, CCHF virus (CCHFV), is classified as a hazard group 4 agent and handled in containment level (CL)-4. In contrast, most endemic ...
Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2016)
Lung cancer is one of the most common mortal cancer types both for men and women. Several different biomarkers have been analyzed to reveal lung cancer prognosis pathways for developing efficient therapeutics and diagnostic ...
Emergency management of severe hyperkalemia: Guideline for best practice and opportunities for the future
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2016)
Hyperkalemia is a common electrolyte disorder, especially in chronic kidney disease, diabetes mellitus, or heart failure. Hyperkalemia can lead to potentially fatal cardiac dysrhythmias, and it is associated with increased ...