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Effects of castration on adrenergic, cholinergic and nonadrenergic, noncholinergic responses of isolated corpus cavernosum from rabbit
(BLACKWELL SCIENCE LTD, 1997)
Objective To investigate the effects of castration and testosterone on the constricting effect of phenylephrine and endothelium-dependent and -independent relaxing effects of different agonists in the corpus cavernosum of ...
Tolerance to isosorbide dinitrate in isolated strips of rabbit corpus cavernosum
(BLACKWELL SCIENCE LTD, 1998)
The aim of this study was to investigate whether prolonged exposure to a high concentration of isosorbide dinitrate (ISDN) would result in tolerance being developed against its relaxant activity in strips of corpus cavernosum, ...
Impaired contraction and relaxation in the aorta of streptozotocin-diabetic rats
(KARGER, 1998)
It is known that diabetes mellitus alters the vascular responsiveness to several vasoconstrictors and vasodilators. Endothelium-derived nitric oxide is a potent endogenous nitrovasodilator, and endothelin-1 (ET-1) is a ...
Effect of endothelin-1 on spontaneous contractions and effects of nimodipine and isradipine on endothelin-1-induced contractions in myometrial strips isolated from normal pregnant and preeclamptic women
(MUNKSGAARD INT PUBL LTD, 1998)
Background. To examine the effect of endothelin-l (ET-1) on spontaneous contractile activity and the effects of nimodipine and isradipine on ET-l-induced contractile responses in myometrial strips isolated from normal ...
Vascular smooth muscle reactivity and endothelium derived relaxing factor in experimental obstructive jaundice
(SWETS ZEITLINGER PUBLISHERS, 1996)
Obstructive jaundice is associated with a predisposition to systemic hypotension and acute renal failure. Altered vascular reactivity may contribute to the development of hypotension. In this experimental study on dogs, ...
Effects of nimodipine and isradipine on endothelin-1-induced contraction of pregnant rat myometrium
(ELSEVIER SCIENCE BV, 1998)
The purpose of this study was to investigate the effect of nimodipine and isradipine on endothelin-1-induced contractions of isolated pregnant rat myometrium. Endothelin-1 at 10(-10)-10(-8) M dose-dependently increased the ...
Effect of deferoxamine and sympathectomy on vasospasm following subarachnoid hemorrhage
(KARGER, 1996)
We examined the effects of subarachnoid hemorrhage (SAH) and treatment with deferoxamine (DFO) or sympathectomy on vascular smooth muscle function, as well as the underlying mechanisms involved, by recording the responses ...
Effects of sympathectomy on endothelin-1 and histamine responses of rabbit carotid artery
(ELSEVIER SCIENCE INC, 1997)
1. The effects of chronic sympathectomy on contractile responses of rabbit common carotid artery was studied in vitro. 2. Endothelin-1 (ET-I), histamine, KCl and papaverine concentration-response curves of sympathectomized ...
The effects of long-term oral administration of L-arginine on the erectile response of rabbits with alloxan-induced diabetes
(BLACKWELL SCIENCE LTD, 1999)
Objective To investigate the effects of the long-term oral administration of L-arginine on the impaired neurogenic and endothelium-dependent relaxation responses of corpus cavernosum smooth muscle from alloxan-induced ...
Effect of additional testosterone on purinergic responses in isolated rabbit corpus cavernosum strips
(ACADEMIC PRESS LTD, 1998)
Recently, it has been demonstrated that the endothelium of corpus cavernosum (CC) plays an important role on smooth muscle relaxation, which is crucial to initiate and maintain erection. We investigated the effect of ...