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Tolerance to isosorbide dinitrate in isolated strips of rabbit corpus cavernosum
(BLACKWELL SCIENCE LTD, 1998)
The aim of this study was to investigate whether prolonged exposure to a high concentration of isosorbide dinitrate (ISDN) would result in tolerance being developed against its relaxant activity in strips of corpus cavernosum, ...
Impaired contraction and relaxation in the aorta of streptozotocin-diabetic rats
(KARGER, 1998)
It is known that diabetes mellitus alters the vascular responsiveness to several vasoconstrictors and vasodilators. Endothelium-derived nitric oxide is a potent endogenous nitrovasodilator, and endothelin-1 (ET-1) is a ...
Effect of endothelin-1 on spontaneous contractions and effects of nimodipine and isradipine on endothelin-1-induced contractions in myometrial strips isolated from normal pregnant and preeclamptic women
(MUNKSGAARD INT PUBL LTD, 1998)
Background. To examine the effect of endothelin-l (ET-1) on spontaneous contractile activity and the effects of nimodipine and isradipine on ET-l-induced contractile responses in myometrial strips isolated from normal ...
Effects of nimodipine and isradipine on endothelin-1-induced contraction of pregnant rat myometrium
(ELSEVIER SCIENCE BV, 1998)
The purpose of this study was to investigate the effect of nimodipine and isradipine on endothelin-1-induced contractions of isolated pregnant rat myometrium. Endothelin-1 at 10(-10)-10(-8) M dose-dependently increased the ...
Effect of additional testosterone on purinergic responses in isolated rabbit corpus cavernosum strips
(ACADEMIC PRESS LTD, 1998)
Recently, it has been demonstrated that the endothelium of corpus cavernosum (CC) plays an important role on smooth muscle relaxation, which is crucial to initiate and maintain erection. We investigated the effect of ...
Changes in the nitric oxide system of rat myometrium during midgestation and delivery at term
(ACADEMIC PRESS LTD, 1998)
The aims of this study were to investigate whether a nitric oxide (NO) system is present in the pregnant rat myometrium and whether it differentially inhibits myometrial contractility during midgestation and delivery at ...
Inhibitory effects of isradipine on spontaneous and oxytocin- and carbachol-stimulated contractions of rat myometrium
(KARGER, 1998)
Our aim was to investigate the effect of isradipine, a second-generation calcium channel blocker, on spontaneous and oxytocin- and carbachol-stimulated contractions of myometrium isolated from nonpregnant and pregnant rats. ...