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dc.contributor.authorKaradayi, Sule
dc.contributor.authorArslan, Sulhattin
dc.contributor.authorSumer, Zeynep
dc.contributor.authorTuran, Mustafa
dc.contributor.authorSumer, Haldun
dc.contributor.authorKaradayi, Kursat
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:59:12Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:59:12Z
dc.date.issued2013
dc.identifier.issn0301-4851
dc.identifier.urihttps://dx.doi.org/10.1007/s11033-013-2565-8
dc.identifier.urihttps://hdl.handle.net/20.500.12418/8619
dc.descriptionWOS: 000322392300004en_US
dc.descriptionPubMed ID: 23645038en_US
dc.description.abstractWe hypothesized that solid tumors rarely occur in patients with hydatid disease. We obtained the serum of 14 patients diagnosed with hydatid disease, the serum of 10 patients who did not have a history of hydatid disease, and the hydatid cyst fluid from six patients. These sera and fluid samples were added at different concentrations to NCI-H209/An1 human lung small cell carcinoma cells and L929 mouse fibroblasts as a control group. Sera of patients with hydatid diseases had cytotoxic effects on NCI-H209/An1 cells, but they did not have cytotoxic effects on fibroblast cells. Sera from healthy subjects did not have a cytotoxic effect on the tumor cell line or control fibroblasts. Cyst fluid, also, did not have toxic effects on the NCI-H209/An1 cell line, but was toxic to fibroblasts up to a 1:32 dilution. Sera from patients with hydatid disease had cytotoxic effects on human small cell lung cancer cells in vitro.en_US
dc.language.isoengen_US
dc.publisherSPRINGERen_US
dc.relation.isversionof10.1007/s11033-013-2565-8en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLung canceren_US
dc.subjectHydatid diseaseen_US
dc.subjectCell lineen_US
dc.subjectCytotoxicityen_US
dc.titleDoes hydatid disease have protective effects against lung cancer?en_US
dc.typearticleen_US
dc.relation.journalMOLECULAR BIOLOGY REPORTSen_US
dc.contributor.department[Karadayi, Sule] Cumhuriyet Univ, Sch Med, Dept Thorac Surg, Sivas, Turkey -- [Arslan, Sulhattin] Cumhuriyet Univ, Sch Med, Dept Chest Dis, Sivas, Turkey -- [Sumer, Zeynep] Cumhuriyet Univ, Sch Med, Dept Microbiol, Sivas, Turkey -- [Turan, Mustafa -- Karadayi, Kursat] Cumhuriyet Univ, Sch Med, Dept Gen Surg, Sivas, Turkey -- [Sumer, Haldun] Cumhuriyet Univ, Sch Med, Dept Publ Hlth, Sivas, Turkeyen_US
dc.identifier.volume40en_US
dc.identifier.issue8en_US
dc.identifier.endpage4704en_US
dc.identifier.startpage4701en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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