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Diagnostic usefulness of pregnancy-associated plasma protein-A in suspected pulmonary embolism

Date

2013

Author

Berk, Serdar
Dogan, Omer Tamer
Aydemir, Eylem Itir
Bingol, Asli
Ozsahin, Sefa Levent
Akkurt, Ibrahim

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Abstract

Background: The role of biomarkers for prognostication and diagnosis of pulmonary embolism (PE) is increasing. It has been reported that pregnancy-associated plasma protein-A (PAPP-A) can be used as a proatherosclerotic marker. The present study was aimed to evaluate whether PAPP-A levels are helpful in the differential diagnosis of patients presenting with suspected PE. Methods: 53 consecutive patients evaluated for suspected PE were prospectively enrolled in the study. Serum PAPP-A levels were measured in the blood samples which were taken at admission. Multi-slice computed tomographic angiography was used to verify the diagnosis of PE. Results: PE was detected in 24 out of the 53 patients, while it was excluded in 29 patients by thorax multi-detector computerized tomography scan. No significant difference was detected in mean serum PAPP-A level between groups (5.72 +/- 0.31 mg/L vs. 5.67 +/- 0.06 mg/L, respectively). Conclusions: Serum PAPP-A level has no role in the evaluation for PE.

Source

MULTIDISCIPLINARY RESPIRATORY MEDICINE

Volume

8

URI

https://dx.doi.org/10.1186/2049-6958-8-49
https://hdl.handle.net/20.500.12418/8632

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  • Makale Koleksiyonu [5200]
  • Makale Koleksiyonu [5745]
  • Öksüz Yayınlar Koleksiyonu - WoS [6162]



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