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dc.contributor.authorCiftel, Sedat
dc.contributor.authorIcagasioglu, Serhat
dc.contributor.authorYildiz, Gursel
dc.contributor.authorTekin, Gonca
dc.contributor.authorAydin, Huseyin
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:03:47Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:03:47Z
dc.date.issued2012
dc.identifier.issn0168-8227
dc.identifier.issn1872-8227
dc.identifier.urihttps://dx.doi.org/10.1016/j.diabres.2011.12.021
dc.identifier.urihttps://hdl.handle.net/20.500.12418/9148
dc.descriptionWOS: 000303668000023en_US
dc.descriptionPubMed ID: 22240157en_US
dc.description.abstractBackground: Early diagnosis of cardiovascular disease in diabetic patients may be important to introduce treatment early. Echocardiography is a method used to show the ventricular functions. A ventricular hormone, BNP is used to identify the changes in the ventricular function in early period. NT-proBNP which is a more stable compound with a longer half-life is used in measurement of BNP. Methods: Left ventricular diastolic dysfunction (LVDD) was detected and NT-proBNP levels were measured in forty-four asymptomatic patients with ages of 30-70 and type 2 DM and control group consisted of 40 healthy individuals from the same age group. Results: NT-proBNP levels were found as 566.7 +/- 738.5 pg/ml in the diabetics with LVDD detected, 166.3 +/- 137.1 pg/ml in the diabetics without LVDD and 134.5 +/- 77.2 pg/ml in the control group. Levels of NT-proBNP were significantly higher in the group with left ventricular diastolic dysfunction (p < 0.05). However, when the levels of NT-proBNP in the diabetic patients without LVDD were compared with the controls, the difference was not significant (p > 0.05). NT-proBNP levels were found significantly higher in LVDD group compared to the controls without a difference between the ejection fractions (p < 0.05). Conclusion: High levels of NT-proBNP was correlated tissue Doppler echocardiography findings in type 2 DM patients with preserved ejection fraction. (C) 2011 Elsevier Ireland Ltd. All rights reserved.en_US
dc.language.isoengen_US
dc.publisherELSEVIER IRELAND LTDen_US
dc.relation.isversionof10.1016/j.diabres.2011.12.021en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLeft ventricular diastolicen_US
dc.subjectdysfunctionen_US
dc.subjectNT-proBNPen_US
dc.subjectTissue Doppler echocardiographyen_US
dc.subjectType 2 diabetes mellitusen_US
dc.titleAssociation of left ventricular diastolic dysfunction with elevated NT-proBNP in type 2 diabetes mellitus patients with preserved ejection fraction: The supplemantary role of tissue doppler imaging parameters and NT-proBNP levelsen_US
dc.typearticleen_US
dc.relation.journalDIABETES RESEARCH AND CLINICAL PRACTICEen_US
dc.contributor.department[Ciftel, Sedat -- Icagasioglu, Serhat] Cumhuriyet Univ, Fac Med, Dept Internal Med, TR-58140 Sivas, Turkey -- [Yildiz, Gursel] Ataturk State Hosp, Dept Internal Med, Div Nephrol, TR-67130 Zonguldak, Turkey -- [Tekin, Gonca] Cumhuriyet Univ, Fac Med, Dept Cardiol, TR-58140 Sivas, Turkey -- [Aydin, Huseyin] Cumhuriyet Univ, Fac Med, Dept Biochem, TR-58140 Sivas, Turkeyen_US
dc.contributor.authorIDciftel, sedat -- 0000-0003-4905-1944en_US
dc.identifier.volume96en_US
dc.identifier.issue2en_US
dc.identifier.endpage186en_US
dc.identifier.startpage179en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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