dc.contributor.author | Ciftel, Sedat | |
dc.contributor.author | Icagasioglu, Serhat | |
dc.contributor.author | Yildiz, Gursel | |
dc.contributor.author | Tekin, Gonca | |
dc.contributor.author | Aydin, Huseyin | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:03:47Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:03:47Z | |
dc.date.issued | 2012 | |
dc.identifier.issn | 0168-8227 | |
dc.identifier.issn | 1872-8227 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.diabres.2011.12.021 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/9148 | |
dc.description | WOS: 000303668000023 | en_US |
dc.description | PubMed ID: 22240157 | en_US |
dc.description.abstract | Background: Early diagnosis of cardiovascular disease in diabetic patients may be important to introduce treatment early. Echocardiography is a method used to show the ventricular functions. A ventricular hormone, BNP is used to identify the changes in the ventricular function in early period. NT-proBNP which is a more stable compound with a longer half-life is used in measurement of BNP. Methods: Left ventricular diastolic dysfunction (LVDD) was detected and NT-proBNP levels were measured in forty-four asymptomatic patients with ages of 30-70 and type 2 DM and control group consisted of 40 healthy individuals from the same age group. Results: NT-proBNP levels were found as 566.7 +/- 738.5 pg/ml in the diabetics with LVDD detected, 166.3 +/- 137.1 pg/ml in the diabetics without LVDD and 134.5 +/- 77.2 pg/ml in the control group. Levels of NT-proBNP were significantly higher in the group with left ventricular diastolic dysfunction (p < 0.05). However, when the levels of NT-proBNP in the diabetic patients without LVDD were compared with the controls, the difference was not significant (p > 0.05). NT-proBNP levels were found significantly higher in LVDD group compared to the controls without a difference between the ejection fractions (p < 0.05). Conclusion: High levels of NT-proBNP was correlated tissue Doppler echocardiography findings in type 2 DM patients with preserved ejection fraction. (C) 2011 Elsevier Ireland Ltd. All rights reserved. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | ELSEVIER IRELAND LTD | en_US |
dc.relation.isversionof | 10.1016/j.diabres.2011.12.021 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Left ventricular diastolic | en_US |
dc.subject | dysfunction | en_US |
dc.subject | NT-proBNP | en_US |
dc.subject | Tissue Doppler echocardiography | en_US |
dc.subject | Type 2 diabetes mellitus | en_US |
dc.title | Association of left ventricular diastolic dysfunction with elevated NT-proBNP in type 2 diabetes mellitus patients with preserved ejection fraction: The supplemantary role of tissue doppler imaging parameters and NT-proBNP levels | en_US |
dc.type | article | en_US |
dc.relation.journal | DIABETES RESEARCH AND CLINICAL PRACTICE | en_US |
dc.contributor.department | [Ciftel, Sedat -- Icagasioglu, Serhat] Cumhuriyet Univ, Fac Med, Dept Internal Med, TR-58140 Sivas, Turkey -- [Yildiz, Gursel] Ataturk State Hosp, Dept Internal Med, Div Nephrol, TR-67130 Zonguldak, Turkey -- [Tekin, Gonca] Cumhuriyet Univ, Fac Med, Dept Cardiol, TR-58140 Sivas, Turkey -- [Aydin, Huseyin] Cumhuriyet Univ, Fac Med, Dept Biochem, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | ciftel, sedat -- 0000-0003-4905-1944 | en_US |
dc.identifier.volume | 96 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.endpage | 186 | en_US |
dc.identifier.startpage | 179 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |