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dc.contributor.authorKaradayi, Sule
dc.contributor.authorSahin, Ekber
dc.contributor.authorNadir, Aydin
dc.contributor.authorTuncer, Ersin
dc.contributor.authorSilig, Yavuz
dc.contributor.authorKorkmaz, Ilhan
dc.contributor.authorTanzer, Fatos
dc.contributor.authorSezer, Hafize
dc.contributor.authorKaptanoglu, Melih
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:03:48Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:03:48Z
dc.date.issued2012
dc.identifier.issn1792-0981
dc.identifier.issn1792-1015
dc.identifier.urihttps://dx.doi.org/10.3892/etm.2012.495
dc.identifier.urihttps://hdl.handle.net/20.500.12418/9155
dc.descriptionWOS: 000303284700010en_US
dc.description.abstractTo assess the wound healing capabilities of damaged lung tissue in the postpartum period, we investigated the parameters related to wound healing in a rat model of lung damage. Rats were divided into six groups: IA, I B, II, IIIA, IIIB and IV (n=7 in each group). Group IA included rats not in the postpartum period that were sacrificed on the third day after lung injury, group IB included rats not in the postpartum period that were sacrificed on the tenth day after lung injury, group II included rats not in the postpartum period that did not receive lung injury, group IIIA included rats in the postpartum period that were sacrificed on the third day after lung injury, group IIIB included rats in the postpartum period that were sacrificed on the tenth day after lung injury and group IV included rats in the postpartum period without lung injury. Wound healing was evaluated histopathologically and measurements of hydroxyproline levels, serum alanine and glutamine were taken. A significant difference in serum alanine levels was evident between groups IA and IIIA. Significant differences were also observed between serum alanine and glutamine levels in groups IB and IIIB. In conclusion, we demonstrated that serum alanine levels were reduced in the postpartum period following lung injury, which may be expected to negatively impact wound healing in this period. The administration of exogenous alanine for traumatic events occurring during the postpartum period may thus contribute positively to wound healing capabilities during this period.en_US
dc.description.sponsorshipCumhuriyet University [T-406]en_US
dc.description.sponsorshipThis work was supported by the Scientific Research Project Fund of Cumhuriyet University, under project number T-406.en_US
dc.language.isoengen_US
dc.publisherSPANDIDOS PUBL LTDen_US
dc.relation.isversionof10.3892/etm.2012.495en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpneumothoraxen_US
dc.subjectraten_US
dc.subjectwound healingen_US
dc.subjectlungen_US
dc.subjectpostpartum perioden_US
dc.titleInvestigation of wound healing in rat lung tissues in the postpartum perioden_US
dc.typearticleen_US
dc.relation.journalEXPERIMENTAL AND THERAPEUTIC MEDICINEen_US
dc.contributor.department[Karadayi, Sule -- Korkmaz, Ilhan] Cumhuriyet Univ, Sch Med, Dept Emergency Med, TR-58140 Sivas, Turkey -- [Sahin, Ekber -- Nadir, Aydin -- Kaptanoglu, Melih] Cumhuriyet Univ, Sch Med, Dept Thorac Surg, TR-58140 Sivas, Turkey -- [Tuncer, Ersin] Cumhuriyet Univ, Sch Med, Dept Pathol, TR-58140 Sivas, Turkey -- [Silig, Yavuz] Cumhuriyet Univ, Sch Med, Dept Biochem, TR-58140 Sivas, Turkey -- [Tanzer, Fatos] Cumhuriyet Univ, Sch Med, Dept Pediat, TR-58140 Sivas, Turkey -- [Sezer, Hafize] Cumhuriyet Univ, Sch Med, Dept Biostat, TR-58140 Sivas, Turkeyen_US
dc.identifier.volume3en_US
dc.identifier.issue5en_US
dc.identifier.endpage810en_US
dc.identifier.startpage807en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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