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dc.contributor.authorTepe, Bektas
dc.contributor.authorMalatyali, Erdogan
dc.contributor.authorDegerli, Serpil
dc.contributor.authorBerk, Seyda
dc.descriptionWOS: 000302814700023en_US
dc.descriptionPubMed ID: 22037826en_US
dc.description.abstractAmoebic keratitis is difficult to treat without total efficacy in some patients because of cysts, which are less susceptible than trophozoites to the usual treatments. The aim of this study is to evaluate the in vitro amoebicidal activity of the methanolic extracts of Teucrium polium and Teucrium chamaedrys. In the presence of methanolic extracts (ranging from 1.0 to 32.0 mg/ml), numbers of the viable Acanthamoeba castellani trophozoites and cysts were decreased during the experimental process. Both extracts showed time- and dose-dependent amoebicidal action on the trophozoites and cysts. Among the extracts tested, T. chamaedrys showed the strongest amoebicidal effect on the trophozoites. In the presence of 16 mg/ml or above extract concentrations, no viable trophozoites were observed within 48 h. In the case of T. polium, no viable trophozoites were observed within 48 h at 32 mg/ml concentration. As expected, cysts were found more resistant to the extracts than the trophozoites.en_US
dc.description.sponsorshipResearch Council of Cumhuriyet University (CUBAP), Sivas-TURKEY [F-346]en_US
dc.description.sponsorshipThis study is financially supported by the Research Council of Cumhuriyet University (CUBAP), Sivas-TURKEY with the project number of F-346.en_US
dc.titleIn vitro amoebicidal activities of Teucrium polium and T. chamaedrys on Acanthamoeba castellanii trophozoites and cystsen_US
dc.relation.journalPARASITOLOGY RESEARCHen_US
dc.contributor.department[Tepe, Bektas -- Berk, Seyda] Cumhuriyet Univ, Dept Mol Biol & Genet, Fac Sci & Literature, TR-58140 Sivas, Turkey -- [Malatyali, Erdogan -- Degerli, Serpil] Cumhuriyet Univ, Dept Parasitol, Sch Med, TR-58140 Sivas, Turkeyen_US
dc.contributor.authorIDTEPE, Bektas -- 0000-0001-8982-5188en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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