dc.contributor.author | Tepe, Bektas | |
dc.contributor.author | Malatyali, Erdogan | |
dc.contributor.author | Degerli, Serpil | |
dc.contributor.author | Berk, Seyda | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:03:49Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:03:49Z | |
dc.date.issued | 2012 | |
dc.identifier.issn | 0932-0113 | |
dc.identifier.uri | https://dx.doi.org/10.1007/s00436-011-2698-4 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/9159 | |
dc.description | WOS: 000302814700023 | en_US |
dc.description | PubMed ID: 22037826 | en_US |
dc.description.abstract | Amoebic keratitis is difficult to treat without total efficacy in some patients because of cysts, which are less susceptible than trophozoites to the usual treatments. The aim of this study is to evaluate the in vitro amoebicidal activity of the methanolic extracts of Teucrium polium and Teucrium chamaedrys. In the presence of methanolic extracts (ranging from 1.0 to 32.0 mg/ml), numbers of the viable Acanthamoeba castellani trophozoites and cysts were decreased during the experimental process. Both extracts showed time- and dose-dependent amoebicidal action on the trophozoites and cysts. Among the extracts tested, T. chamaedrys showed the strongest amoebicidal effect on the trophozoites. In the presence of 16 mg/ml or above extract concentrations, no viable trophozoites were observed within 48 h. In the case of T. polium, no viable trophozoites were observed within 48 h at 32 mg/ml concentration. As expected, cysts were found more resistant to the extracts than the trophozoites. | en_US |
dc.description.sponsorship | Research Council of Cumhuriyet University (CUBAP), Sivas-TURKEY [F-346] | en_US |
dc.description.sponsorship | This study is financially supported by the Research Council of Cumhuriyet University (CUBAP), Sivas-TURKEY with the project number of F-346. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | SPRINGER | en_US |
dc.relation.isversionof | 10.1007/s00436-011-2698-4 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.title | In vitro amoebicidal activities of Teucrium polium and T. chamaedrys on Acanthamoeba castellanii trophozoites and cysts | en_US |
dc.type | article | en_US |
dc.relation.journal | PARASITOLOGY RESEARCH | en_US |
dc.contributor.department | [Tepe, Bektas -- Berk, Seyda] Cumhuriyet Univ, Dept Mol Biol & Genet, Fac Sci & Literature, TR-58140 Sivas, Turkey -- [Malatyali, Erdogan -- Degerli, Serpil] Cumhuriyet Univ, Dept Parasitol, Sch Med, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | TEPE, Bektas -- 0000-0001-8982-5188 | en_US |
dc.identifier.volume | 110 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.endpage | 1778 | en_US |
dc.identifier.startpage | 1773 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |