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dc.contributor.authorCelik, V. Kenan
dc.contributor.authorSari, Ismail
dc.contributor.authorBakir, Sevtap
dc.contributor.authorEngin, Aynur
dc.contributor.authorBakir, Deniz
dc.contributor.authorSari, Musa
dc.contributor.authorPoyraz, Omer
dc.contributor.authorYildiz, Gursel
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:05:22Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:05:22Z
dc.date.issued2011
dc.identifier.issn1682-024X
dc.identifier.urihttps://hdl.handle.net/20.500.12418/9503
dc.descriptionWOS: 000296024900024en_US
dc.description.abstractObjective: To determine the levels of and the relationship between serum amyloid A (SAA), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in patients with acute brucellosis. Methodology: SAA, CRP and ESR were measured with ELISA, nephelometry and Mix-Rate x100 vital diagnostic device, respectively, in serum samples of 30 patients diagnosed with acute brucellosis and 40 volunteers with no systemic diseases. Results: Statistically significant difference was determined between patients and controls in terms of the levels of SAA, CRP and ESR (p<0.05). Although CRP levels and ESR were significantly correlated in the patient group (p<0.05), there was no significant correlation between CRP and SAA or ESR and SAA (p>0.05). Conclusion: CRP levels are significantly elevated in bacterial infections, however the increase is minimal in viral infections. SAA increases sooner and to greater levels during the course of infections. In addition, contrary to CRP, SAA is markedly elevated in both bacterial and viral infection. Consequently, these three acute phase reactants should be used together in order to obtain more reliable results in the differential diagnosis of infections.en_US
dc.language.isoengen_US
dc.publisherPROFESSIONAL MEDICAL PUBLICATIONSen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute brucellosisen_US
dc.subjectSerum amyloid Aen_US
dc.subjectC-reactive proteinen_US
dc.subjectErythrocyte sedimentation rateen_US
dc.subjectAcute phase reactanten_US
dc.titleErythrocyte Sedimentation Rate, Serum Amyloid A and C-reactive Protein Levels in Patients with Acute Brucellosisen_US
dc.typearticleen_US
dc.relation.journalPAKISTAN JOURNAL OF MEDICAL SCIENCESen_US
dc.contributor.department[Celik, V. Kenan -- Sari, Ismail -- Bakir, Sevtap -- Bakir, Deniz] Cumhuriyet Univ, Sch Med, Dept Biochem, Sivas, Turkey -- [Engin, Aynur] Cumhuriyet Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Sivas, Turkey -- [Poyraz, Omer] Cumhuriyet Univ, Sch Med, Dept Microbiol & Clin Microbiol, Sivas, Turkey -- [Yildiz, Gursel] Cumhuriyet Univ, Sch Med, Dept Nephrol, Sivas, Turkey -- [Sari, Musa] Cumhuriyet Univ, Fac Sci, Dept Biol, Sivas, Turkeyen_US
dc.contributor.authorIDSari, Ismail -- 0000-0003-3732-2102en_US
dc.identifier.volume27en_US
dc.identifier.issue4en_US
dc.identifier.endpage826en_US
dc.identifier.startpage823en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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