dc.contributor.author | Erdogan, Haydar | |
dc.contributor.author | Ozec, Ayse Vural | |
dc.contributor.author | Caner, Cengiz | |
dc.contributor.author | Toker, Mustafa Ilker | |
dc.contributor.author | Arici, Mustafa Kemal | |
dc.contributor.author | Topalkara, Aysen | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:05:42Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:05:42Z | |
dc.date.issued | 2011 | |
dc.identifier.issn | 1672-5123 | |
dc.identifier.uri | https://dx.doi.org/10.3980/j.issn.2222-3959.2011.02.17 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/9559 | |
dc.description | WOS: 000289913400017 | en_US |
dc.description | PubMed ID: 22553640 | en_US |
dc.description.abstract | AIM: To evalaute the effect of fixed-combination latanoprost 0.005% /timolol maleate 0.5% and dorzolamide hydrochloride 2% /timolol maleate 0.5% on postoperative intraocular pressure after phacoemulsification cataract surgery. METHODS: This study is a prospective, randomized, double-masked and placebo-controlled. The study included 90 eyes of 90 patients which were scheduled to have phacoemulsification surgery. Patients were randomly assigned preoperatively to 1 of 3 groups (30 eyes of 30 patients). Two hour before surgery, the patients received one drop latanoprost/timolol (group 1), dorzolamide/timolol (group 2) and placebo (group 3, control group). The IOPs were measured at preoperative and postoperative 4, 8, and 24 hours. RESULTS: The preoperative mean intraocular pressure was not statistically significant between both drug groups and control group. In group 1 and 2, the postoperative mean TOP [group1: (14.03 +/- 3.15)mmHg and group 2: (14.16 +/- 4.43) mmHg] at 24 hours were significantly lower than the control group [(16.93 +/- 3.70)mmHg, (P < 0.05)]. In addition, the postoperative mean IOP of group 1 [(14.90? .69)mmHg] at 8 hours was significantly lower than the control group [(17.70 +/- 3.89)mmHg, (P < 0.05)], but there was no significant difference between group 2 [(16.16 +/- 5.23)mmHg] and control group at 8 hours (P > 0.05). CONCLUSION: When compared with placebo, the use of preoperative fixed combination of latanoprost/timolol and dorzolamide/timolol is an effective method for preventing intraocular pressure elevation in 24 hours after phacoemulsification surgery, but did not completely prevent TOP spikes. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | IJO PRESS | en_US |
dc.relation.isversionof | 10.3980/j.issn.2222-3959.2011.02.17 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | dorzolamide/timolol | en_US |
dc.subject | latanoprost/timolol | en_US |
dc.subject | intraocular pressure | en_US |
dc.subject | phacoemulsification | en_US |
dc.subject | cataract surgery | en_US |
dc.title | Effect of latanoprost/timolol and dorzolamide/tiomolol on intraocular pressure after phacoemulsification surgery | en_US |
dc.type | article | en_US |
dc.relation.journal | INTERNATIONAL JOURNAL OF OPHTHALMOLOGY | en_US |
dc.contributor.department | [Erdogan, Haydar -- Ozec, Ayse Vural -- Caner, Cengiz -- Toker, Mustafa Ilker -- Arici, Mustafa Kemal -- Topalkara, Aysen] Univ Cumhuriyet, Dept Ophthalmol, Sch Med, TR-58140 Sivas, Turkey | en_US |
dc.contributor.authorID | arici, mustafa kemal -- 0000-0002-6350-9723 | en_US |
dc.identifier.volume | 4 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.endpage | 194 | en_US |
dc.identifier.startpage | 190 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |