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Extrapulmonary involvement in patients with sarcoidosis in Turkey

Date

2011

Author

Okumus, Gulfer
Musellim, Benan
Cetinkaya, Erdogan
Turker, Hatice
Uzaslan, Esra
Yenturk, Esin
Uzun, Oguz
Saglam, Leyla
Kumbasar, Ozlem Ozdemir
Celik, Gokhan
Annakkaya, Ali Nihat
Altiay, Gundeniz
Tabak, Levent
Sakar, Aysin
Kiter, Goksel
Erturan, Serdar
Turktas, Haluk
Yalniz, Enver
Akkoclu, Atilla
Ogus, Candan
Dogan, Omer Tamer
Ozkan, Metin
Aktogu, Serir
Uzel, Isil
Ongen, Gul

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Abstract

Background and objective: Extrapulmonary sarcoidosis is common, and is almost always associated with concomitant thoracic involvement. Extrapulmonary manifestations vary on the basis of gender, age at presentation and ethnicity. The aim of this study was to investigate extrapulmonary involvement in patients with sarcoidosis in Turkey. Methods: This study was conducted by Turkish Thoracic Society Clinical Problems Study Group. New cases of sarcoidosis between 1 June 2004 and 31 May 2006 were recorded on electronic case record forms sent to all potential investigators and information about extrapulmonary involvement was collected. Results: One hundred and nineteen of 293 patients (83 female, 36 male, mean age = 45 +/- 12 years) had extrapulmonary involvement in this study (40.6%). The median time to diagnosis was 6 months and this was longer than patients with just thoracic sarcoidosis (P = 0.001). Extrapulmonary symptoms were present in 181 (61.8%) patients, and skin lesions, arthralgia and back pain were the commonest (33.4%, 20.8% and 16.4%, respectively). Incidence of organ involvement was independent of age with the exception of ocular involvement, which was higher in those under the age of 40 years (P = 0.007). Conclusions: Skin and peripheral lymph node involvement were the most common sites of extrapulmonary involvement and ocular involvement was more common in those under the age of 40 years in patients with sarcoidosis in a Turkish population.

Source

RESPIROLOGY

Volume

16

Issue

3

URI

https://dx.doi.org/10.1111/j.1440-1843.2010.01878.x
https://hdl.handle.net/20.500.12418/9572

Collections

  • Makale Koleksiyonu [5200]
  • Makale Koleksiyonu [5745]
  • Öksüz Yayınlar Koleksiyonu - WoS [6162]



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