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dc.contributor.authorSahin, Ekber
dc.contributor.authorElagoz, Sahande
dc.contributor.authorCelik, Burcin
dc.contributor.authorNadir, Aydin
dc.contributor.authorKaradayi, Sule
dc.contributor.authorAkkas, Yucel
dc.contributor.authorKaptanoglu, Melih
dc.contributor.authorManduz, Sinasi
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:06:45Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:06:45Z
dc.date.issued2011
dc.identifier.issn1301-5680
dc.identifier.urihttps://hdl.handle.net/20.500.12418/9715
dc.descriptionWOS: 000286413200012en_US
dc.description.abstractBackground: In this study, we investigated the effects of chlorhexidine gluconate and silver nitrate on the lungs and determine their utility in operations for pulmonary hydatid cysts. Methods: Thirty New Zealand Wistar albino rabbits weighing between 2750 and 3000 grams were used in the study and divided into three groups. In the first (control) group, normal saline (0.09% NaCl); in the second group, silver nitrate (0.5%); and in the third group, chlorhexidine gluconate (0.04%) was administered intrathraceally. Thirty days after the procedure, the tracheobronchial and parenchymal changes in the subjects were evaluated histopathologically. Tracheobronchial changes were evaluated with respect to tracheal pathology whereas peribronchial lymphocytic infiltration and parenchymal changes were evaluated with respect to interstitial lymphocytic infiltration, hemorrhage-edema, fibrosis and pneumonitis. Results: The rate of interstitial lymphocytic infiltration was higher in the chlorhexidine gluconate group than in the control group, and the rates of fibrosis and fibrin accumulation were higher in the silver nitrate group than in the control group. No statistically significant differences in other parameters were found between the groups. Conclusion: The results of the study indicate that chlorhexidine gluconate (0.04%) has minimal negative effects on the rabbit lung and tracheobronchial mucosa and is a more reliable agent than silver nitrate.en_US
dc.description.sponsorshipCumhuriyet University Scientific Research Foundation [CUBAP T-321]en_US
dc.description.sponsorshipThis work was supported by the Cumhuriyet University Scientific Research Foundation (CUBAP T-321).en_US
dc.language.isoengen_US
dc.publisherEKIN TIBBI YAYINCILIK LTD STI-EKIN MEDICAL PUBLen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChlorhexidine gluconateen_US
dc.subjecthydatid cysten_US
dc.subjectpulmonaryen_US
dc.subjectsilver nitrateen_US
dc.titleThe effects of chlorhexidine gluconate and silver nitrate on rabbit lung: an experimental studyen_US
dc.typearticleen_US
dc.relation.journalTURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERYen_US
dc.contributor.department[Sahin, Ekber -- Celik, Burcin -- Nadir, Aydin -- Akkas, Yucel -- Kaptanoglu, Melih] Cumhuriyet Univ, Fac Med, Dept Thorac Surg, Sivas, Turkey -- [Elagoz, Sahande] Cumhuriyet Univ, Fac Med, Dept Pathol, Sivas, Turkey -- [Karadayi, Sule] Cumhuriyet Univ, Fac Med, Dept Emergency, Sivas, Turkey -- [Manduz, Sinasi] Cumhuriyet Univ, Fac Med, Dept Cardiovasc Surg, Sivas, Turkeyen_US
dc.identifier.volume19en_US
dc.identifier.issue1en_US
dc.identifier.endpage71en_US
dc.identifier.startpage67en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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