dc.contributor.author | Sahin, Ekber | |
dc.contributor.author | Elagoz, Sahande | |
dc.contributor.author | Celik, Burcin | |
dc.contributor.author | Nadir, Aydin | |
dc.contributor.author | Karadayi, Sule | |
dc.contributor.author | Akkas, Yucel | |
dc.contributor.author | Kaptanoglu, Melih | |
dc.contributor.author | Manduz, Sinasi | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:06:45Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:06:45Z | |
dc.date.issued | 2011 | |
dc.identifier.issn | 1301-5680 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/9715 | |
dc.description | WOS: 000286413200012 | en_US |
dc.description.abstract | Background: In this study, we investigated the effects of chlorhexidine gluconate and silver nitrate on the lungs and determine their utility in operations for pulmonary hydatid cysts. Methods: Thirty New Zealand Wistar albino rabbits weighing between 2750 and 3000 grams were used in the study and divided into three groups. In the first (control) group, normal saline (0.09% NaCl); in the second group, silver nitrate (0.5%); and in the third group, chlorhexidine gluconate (0.04%) was administered intrathraceally. Thirty days after the procedure, the tracheobronchial and parenchymal changes in the subjects were evaluated histopathologically. Tracheobronchial changes were evaluated with respect to tracheal pathology whereas peribronchial lymphocytic infiltration and parenchymal changes were evaluated with respect to interstitial lymphocytic infiltration, hemorrhage-edema, fibrosis and pneumonitis. Results: The rate of interstitial lymphocytic infiltration was higher in the chlorhexidine gluconate group than in the control group, and the rates of fibrosis and fibrin accumulation were higher in the silver nitrate group than in the control group. No statistically significant differences in other parameters were found between the groups. Conclusion: The results of the study indicate that chlorhexidine gluconate (0.04%) has minimal negative effects on the rabbit lung and tracheobronchial mucosa and is a more reliable agent than silver nitrate. | en_US |
dc.description.sponsorship | Cumhuriyet University Scientific Research Foundation [CUBAP T-321] | en_US |
dc.description.sponsorship | This work was supported by the Cumhuriyet University Scientific Research Foundation (CUBAP T-321). | en_US |
dc.language.iso | eng | en_US |
dc.publisher | EKIN TIBBI YAYINCILIK LTD STI-EKIN MEDICAL PUBL | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Chlorhexidine gluconate | en_US |
dc.subject | hydatid cyst | en_US |
dc.subject | pulmonary | en_US |
dc.subject | silver nitrate | en_US |
dc.title | The effects of chlorhexidine gluconate and silver nitrate on rabbit lung: an experimental study | en_US |
dc.type | article | en_US |
dc.relation.journal | TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY | en_US |
dc.contributor.department | [Sahin, Ekber -- Celik, Burcin -- Nadir, Aydin -- Akkas, Yucel -- Kaptanoglu, Melih] Cumhuriyet Univ, Fac Med, Dept Thorac Surg, Sivas, Turkey -- [Elagoz, Sahande] Cumhuriyet Univ, Fac Med, Dept Pathol, Sivas, Turkey -- [Karadayi, Sule] Cumhuriyet Univ, Fac Med, Dept Emergency, Sivas, Turkey -- [Manduz, Sinasi] Cumhuriyet Univ, Fac Med, Dept Cardiovasc Surg, Sivas, Turkey | en_US |
dc.identifier.volume | 19 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.endpage | 71 | en_US |
dc.identifier.startpage | 67 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |