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dc.contributor.authorHizel, Selda
dc.contributor.authorOzden, Ali
dc.contributor.authorTanzer, Fatos
dc.contributor.authorKisa, Ucler
dc.contributor.authorMisirlioglu, Emine Dibek
dc.contributor.authorBuyukkayhan, Derya
dc.contributor.authorKisa, Ozgul
dc.descriptionWOS: 000283606200001en_US
dc.descriptionPubMed ID: 20872322en_US
dc.description.abstractBackground/aims: The aim of this prospective study was to determine the seroprevalence rates of Helicobacter pylori in mother and infant pairs and to discuss the possible fecal-oral transmission route of Helicobacter pylori infection in the early years of life. Methods: Forty-eight mother-child pairs were followed for 12 months. Helicobacter pylori IgG and hepatitis A virus (HAV) IgG levels were measured in maternal sera, infant sera and breast-milk samples at birth and in breast-milk samples and infant sera at follow-up visits. Results: At birth, the rate of Helicobacter pylori positivity was 81.25% in breast-milk and 95.8% in maternal and infant sera. Although there was a decrease in seropositivity in both baby sera and breast-milk at the age of nine months, an increase was observed in the 12(th) month. Hepatitis A virus IgG was measured to show whether Helicobacter pylori and hepatitis A virus use the same transmission routes. Hepatitis A was positive in all infants' sera, in 95.8% of mothers' sera, and in 68.75% of breast-milk samples. Seropositivity rates in infants whose mothers were seropositive for Helicobacter pylori and hepatitis A virus decreased gradually. There was an increase after the 9(th) month of life. Conclusions: Helicobacter pylori seroprevalence rates are high in Anatolia. It is possible that the decrease in breastfeeding with increased introduction of supplemental foods may lead to an increased risk of exposure to Helicobacter pylori.en_US
dc.description.sponsorshipCarmosan 1<SUP>st</SUP> Scientific Researches and Projects Competitionen_US
dc.description.sponsorshipThis study was granted by Carmosan 1<SUP>st</SUP> Scientific Researches and Projects Competition, 1998. We would like to express our special thanks to Prof. Dr. Ender Pehlivanoglu for encouraging us in each phase of the study.en_US
dc.subjectHelicobacter pylorien_US
dc.subjecthepatitis A virusen_US
dc.titleHelicobacter pylori infection in mother and infant pairs in Anatoliaen_US
dc.contributor.department[Hizel, Selda -- Misirlioglu, Emine Dibek] Kirikkale Univ, Sch Med, Dept Pediat, Kirikkale, Turkey -- [Kisa, Ucler -- Kisa, Ozgul] Kirikkale Univ, Sch Med, Dept Biochem, Kirikkale, Turkey -- [Ozden, Ali] Ankara Univ, Sch Med, Dept Gastroenterol, TR-06100 Ankara, Turkey -- [Tanzer, Fatos -- Buyukkayhan, Derya] Cumhuriyet Univ, Sch Med, Dept Pediat, Sivas, Turkey -- Gulhane Mil Med Acad, Dept Microbiol, Ankara, Turkeyen_US
dc.contributor.authorIDKISA, UCLER -- 0000-0002-8131-6810en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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