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dc.contributor.authorKilicli, Fatih
dc.contributor.authorDokmetas, Sebila
dc.contributor.authorCandan, Ferhan
dc.contributor.authorOzsahin, Sefa
dc.contributor.authorKorkmaz, Serdal
dc.contributor.authorAmasyali, Elvan
dc.contributor.authorFakioglu, Koray
dc.contributor.authorDal, Kuersat
dc.contributor.authorAcibucu, Fettah
dc.contributor.authorCakir, Ilkay
dc.descriptionWOS: 000276897900001en_US
dc.descriptionPubMed ID: 20408753en_US
dc.description.abstractIntroduction. Plasma carnitine insufficiency has been known to cause muscle weakness. Carnitine levels and pulmonary functions were lower in patients with diabetes. Patients and Methods. To determine whether pulmonary functions are correlated with carnitine levels in patients with type 2 diabetes. In this study, we evaluated pulmonary functions and carnitine concentrations in 49 patients with type 2 diabetes and 34 healthy controls. Results. Carnitine levels were lower in type 2 diabetes group than control group (52.56 +/- 12.38 and 78.96 +/- 10.66 hmol/mL, respectively, p < 0.0001). Pulmonary functions were not significantly different between groups. Carnitine levels were not correlated with age, duration of diabetes, fasting blood glucose levels, and glycemic control (HbA1c%) in patients with type 2 diabetes. However, carnitine levels in patient group were correlated with % forced vital capacity (FVC%) (r = 0.35, p = 0.016), % forced expiratory volume in 1 s (FEV1%) (r = 0.318, p= 0.029), FEV1/FVC (r= 0.302, p= 0.039), inspiratory muscle strength (PImax) (r = 0.407, p = 0.023), and PImax% (r = 0.423, p= 0.018). Conclusion. This study suggests that low carnitine levels may be associated with lower PImax and PImax% in type 2 diabetes.</.en_US
dc.publisherTAYLOR & FRANCIS INCen_US
dc.subjectType 2 Diabetesen_US
dc.subjectPulmonary Functionsen_US
dc.titleInspiratory Muscle Strength is Correlated with Carnitine Levels in Type 2 Diabetesen_US
dc.relation.journalENDOCRINE RESEARCHen_US
dc.contributor.department[Kilicli, Fatih -- Dokmetas, Sebila] Cumhuriyet Univ, Dept Endocrinol, Fac Med, TR-58140 Sivas, Turkey -- [Candan, Ferhan] Cumhuriyet Univ, Dept Nephrol, Fac Med, TR-58140 Sivas, Turkey -- [Ozsahin, Sefa] Cumhuriyet Univ, Dept Chest Dis, Fac Med, TR-58140 Sivas, Turkey -- [Korkmaz, Serdal -- Amasyali, Elvan -- Fakioglu, Koray -- Dal, Kuersat -- Acibucu, Fettah -- Cakir, Ilkay] Cumhuriyet Univ, Dept Internal Med, Fac Med, TR-58140 Sivas, Turkeyen_US
dc.contributor.authorIDKorkmaz, Serdal -- 0000-0002-5759-2735en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

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