Sivas Cumhuriyet Universitesi: Recent submissions
Now showing items 441-460 of 14382
-
Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives
(19 Jan 202)Pathological angiogenesis plays a critical role in tumorigenesis and tumor pro gression, and anti-angiogenesis therapies have evinced promising antitumor effects in solid tumors. Chalcone skeleton has been regarded as a ... -
Clinical value of serum BMP-4, BMP-2, GDF-15, MMP-9, GP39 levels in pregnant women with obesity and the related comorbidities diabetes mellitus and gestational hypertension
(Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany, 2023/2)Abstract Aims We evaluated the clinical value of selected serum biomarkers BMP-4, BMP-2, GDF-15, MMP-9, and GP39 in pregnant women with obesity and the comorbidities diabetes mellitus (DM) and gestational hypertension ... -
Anticancer activity of Heat Shock Protein 70 (HSP70) Inhibitor, JG-98, against human cervical cancer HeLa and ovarian cancer SKOV-3 cells
(Medicine Science International Medical Journal, 2023/3/1)Abstract Cervical and ovarian cancer are two aggressive neoplasms for women, still with high mortality and morbidity. Among the molecules and compounds that have anticancer activity, it was studied the JG-98, a heat shock ... -
Zonulin as a potential biomarker for diminished ovarian reserve: A prospective study
(2023/6)Objective: The purpose of this research is to investigate the relationship between zonulin levels and diminished ovarian reserve (DOR), and to evaluate the potential role of autoimmunity in the development of DOR. The ... -
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death/Otofaji ile iliskili hucrelerde subkutan endometriozis fare modelinde metformin ve genireliksin etkisi.
(Galenos Yayinevi Tic. Ltd., Eylül/2023)Objective This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model. Materials and Methods Five groups were formed with eight ... -
Use of newly synthetized magnetic Fe3O4 nanoparticles modified with hexadecyl trimethyl ammonium bromide for the sensitive analysis of antidepressant drugs, duloxetine and vilazodone in wastewater and urine samples
(17 Haziran)A new enrichment and determination method involving HPLC-DAD analysis following magnetic solid-phase extraction (MSPE) was developed to detect trace amounts of two antidepressant drugs, namely, duloxetine (DUL) and vilazodone ... -
Use of Fe3O4@MPTMS-Dithizone Magnetic Nanoparticles as Solid Phase Sorbent for Sensitive Analysis of Sibutramine Molecules in Herbal Slimming Products
(Haziran 20)Background: A new enrichment and sensitive determination method, which includes HPLCDAD analysis after Magnetic Solid Phase Extraction (MSPE), has been developed for trace analysis of Sibutramine molecules in herbal ... -
Azinphos-methyl and chlorfenvinphos pesticides determination using fabric phase sorptive extraction followed by high performance liquid chromatography-photodiode array detector
(Ağustos 20)A reliable and efficient fabric phase sorptive extraction method was developed for the rapid analysis of azinphos-methyl and chlorfenvinphos pesticide residues in wastewater and fruit juice samples using high-performance ... -
Green synthesis of reduced graphene oxide and their use on column adsorption of phenol from olive mill wastewater
(2023)A novel reduced graphene oxide (RGO) synthesis using Verbena officinalis as a green, reducing agent was outreaching. RGO was encapsulated in sodium alginate (SA) by cross-linking (SA-RGO beads). SA-RGO beads have been ... -
Collaborative Clinical Research on Metabolomics
(23.10.2023)Metabolomikler nelerdir ve ilişkili klinik durumların güncel literatür eşliğinde araştırılması. Metabolomik analizlerin bu klinik durumlardaki hücresel yollakların araştırılması. -
Synthesis and Molecular Docking of New N-Acyl Hydrazones- Benzimidazole as hCA I and II Inhibitors
(20.01.2023)Background: The carbonic anhydrases (CAs) which are found in most living organisms is a member of the zinc-containing metalloenzyme family. The abnormal levels and activities are frequently associated with various diseases ... -
Synthesis, and docking studies of novel tetrazole-S-alkyl derivatives as antimicrobial agents
(07.01.2023)A series of novel tetrazole-S-alkyl-piperazine derivatives were synthesized and evaluated for their antifungal activity against C. albicans (ATCC 24433), C. krusei (ATCC 6258) and C. parapsilosis (ATCC 22019) and ... -
Metabolomics in the Diagnosis of Pregnancy Complications
(2023/2)The pregnancy process is an intricate and unique period that requires control examinations to ensure the continuity of the well-being of the mother and the baby. The accompanying changes are also evident biologically, ... -
IMMUNOTHERAPY IN CANCER TREATMENT
(31.06.2023)Cancer, which causes the death of approximately 10 million people every year, is a type of disease that begins to spread to other parts of the body by uncontrolled proliferation of cells in the tissues and organs of our ... -
Nekroz
(31.12.2023)Nekroz, hücrenin ani bir şok (radyasyon, ısı, kimyasallar, hipoksi, iskemi vb.), mekanik stres gibi şiddetli çevresel bozulmalar ve donma-çözülme sonrası gibi ciddi şekilde hasar gördüğü, enerjiden bağımsız bir hücre ... -
Synthesis, biological evaluation and in silico studies of novel thiadiazole-hydrazone derivatives for carbonic anhydrase inhibitory and anticancer activities
(04.08.2023)ABSTRACT Thiadiazole and hydrazone derivatives (5a–5i) were synthesized and their chemical structures were verified and described by 1 H NMR, 13 C NMR, and HRMS spectra. Three cancer cell lines (MCF-7, MDA, and ... -
Dilay KARADEMİR, Mustafa KARADEMİR, İrem KÜÇÜKYILDIZ, Nazan YURTÇU, İlkin Seda CAN, Esra GÜLTÜRK
(2023/3/3)Abstract Amaç: Bu çalışmada amaç epilepsi tanısı almış ve antiepileptik ilaç kullanan gebelerde epilepsi hastalığının ve uygulanan antiepileptik tedavi protokolünün, anne, fetüs ve yenidoğan üzerine etkisinin değerlendi ... -
The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum
(2023/9/30)ABSTRACT History Received: 11/04/2023 Accepted: 22/09/2023 Hyperemesis gravidarum (HG) has severe, dramatic consequences, and the cause of this severe disease has not yet been determined clearly. It is known that ... -
Thickness-Dependent Charge Transport in Three Dimensional Ru(II)− Tris(phenanthroline)-Based Molecular Assemblies
(2023)We describe here the fabrication of large-area molecular junctions with a configuration of ITO/[Ru(Phen)3]/Al to understand temperature- and thickness-dependent charge transport phenomena. Thanks to the electrochemical ... -
Determination of oxidative stability of different vegetable oils by means of middle infrared spectroscopy and DFT calculations
(Elsevier, 2023)Oxidative stability is one of the most important quality parameters of vegetable oils. This study aims to determine oxidative stability of five different vegetable oils by means of infrared spectroscopy combined with DFT ...