Cytotoxic activity of zinc oxide/titanium dioxide nanoparticles on prostate cancer cells

Basit Öğe Kaydı
dc.contributor.authorTaş, Ayça
dc.contributor.authorÇakmak, Neşe Keklikcioğlu
dc.contributor.authorAgbektas, Tugba
dc.contributor.authorSiliğ, Yavuz
dc.date.accessioned2024-10-26T17:41:20Z
dc.date.available2024-10-26T17:41:20Z
dc.date.issued2019
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractProstate cancer is caused by uncontrolled growth of cells in the prostate gland. The aim of this study was to determine the cytotoxic activity of titanium dioxide (TiO2) and zinc oxide (ZnO) nanoparticles (NPs) and TiO2 + ZnO nanocomposite (NC) in human prostate cancer cell line (DU-145) and healthy mouse fibroblast cell line (L-929). In the study, TiO2 and ZnO NPs and TiO2 + ZnO NC were synthesized. Cytotoxic activities of NC and NPs was then analyzed in human prostate cancer cell line (DU-145) and healthy mouse fibroblast cell lines (L-929) using the MTT method. TiO2, ZnO and TiO2 + ZnO IC50 values were determined in DU-145 and L-929 cell cells (n = 6). TiO2 + ZnO NC in the Du-145 cell line was found as the most active, having statistically significant (***p < 0.0001, **p ? 0.001 and **p ? 0.01).
dc.identifier.doi10.32571/ijct.613536
dc.identifier.endpage120
dc.identifier.issn2602-277X
dc.identifier.issue2
dc.identifier.startpage113
dc.identifier.trdizinid390001
dc.identifier.urihttps://doi.org/10.32571/ijct.613536
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/390001
dc.identifier.urihttps://hdl.handle.net/20.500.12418/24462
dc.identifier.volume3
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofInternational Journal of Chemistry and Technology (IJCT)
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleCytotoxic activity of zinc oxide/titanium dioxide nanoparticles on prostate cancer cells
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu