The role of inflammatory markers in the diagnosis and follow-up of diabetic foot osteomyelitis

Basit Öğe Kaydı
dc.contributor.authorDurmaz, Burak
dc.contributor.authorYılmaz, Sarper
dc.contributor.authorDerebaşınlıoğlu, Handan
dc.date.accessioned2024-10-26T17:43:10Z
dc.date.available2024-10-26T17:43:10Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractAbstractAim: Diabetic foot infections are a major cause of mortality and morbidity in diabetic patients. These mortality and mortality rates increase further when osteomyelitis develops. Simple techniques are needed to facilitate the diagnosis and follow-up of diabetic foot osteomyelitis.Material and Methods: Eighty-nine patients who underwent amputation due to diabetic foot between January 2012 and May 2017 were included in the study. The patients were grouped as those with or without osteomyelitis according to their pathology results. C-reactive protein (CRP) level and erythrocyte sedimentation rate (ESR) were assessed pre- and postoperatively. Results: Preoperative ESR values were significantly higher in the osteomyelitis group (p<0.05), but there was no statistically difference in CRP (p>0.05). Comparison of preoperative, postoperative 2-week, and postoperative 1-month ESR values showed a statistical difference among all time points (p<0.05), with lower postoperative values compared to preoperative values. At a cut-off value of 55.5 mm/h, preoperative ESR had sensitivity of 95.3% and specificity of 87.5% in the discrimination of patients with and without osteomyelitis.Conclusion: ESR is a simple, rapid, and cost-effective diagnostic marker with high sensitivity and specificity in the diagnosis of diabetic foot osteomyelitis. However, monitoring CRP values may be superior to ESR when evaluating early treatment response.
dc.identifier.doi10.5455/annalsmedres.2019.11.694
dc.identifier.endpage1081
dc.identifier.issn2636-7688
dc.identifier.issue4
dc.identifier.startpage1077
dc.identifier.trdizinid361908
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2019.11.694
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/361908
dc.identifier.urihttps://hdl.handle.net/20.500.12418/25055
dc.identifier.volume27
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleThe role of inflammatory markers in the diagnosis and follow-up of diabetic foot osteomyelitis
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu