The effect of a biphasic ceramic on calvarial bone regeneration in rats.

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dc.contributor.authorDevelioglu, Hakan
dc.contributor.authorKoptagel, Emel
dc.contributor.authorGedik, Rüştü
dc.contributor.authorDupoirieux, Laurent
dc.date.accessioned2024-10-26T17:51:49Z
dc.date.available2024-10-26T17:51:49Z
dc.date.issued2005
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractBioactive ceramics (calcium phosphate ceramics, hydroxyapatite ceramics) are now extensively used in oral surgery. The purpose of this study was to assess the effect of a new biphasic ceramic (Ceraform) on the osteogenesis in a rat calvarial defect model. Fifteen Wistar rats were used in this study. Two symmetrical 3-mm wide defects were created in the skull of each rat. The left defect was left empty as a control and the right defect was filled with the ceramic. The rats were sacrificed at day 30, and the calvarial specimens were processed for qualitative and quantitative histological examinations. The material exhibited no adverse effects, but no bone healing was noted either. No statistical difference regarding bone regeneration was observed between the 2 defects (P > .05). This study showed that Ceraform did not elicit any inflammatory reaction; however, it had no effect on bone regeneration, and this material seems suitable only as a space-maintaining material.
dc.identifier.doi10.1563/1548-1336(2005)31[309:TEOABC]2.0.CO;2
dc.identifier.endpage312
dc.identifier.issn0160-6972
dc.identifier.issue6
dc.identifier.pmid2006117499
dc.identifier.scopus2-s2.0-33646093749
dc.identifier.scopusqualityQ2
dc.identifier.startpage309
dc.identifier.urihttps://doi.org/10.1563/1548-1336(2005)31[309:TEOABC]2.0.CO;2
dc.identifier.urihttps://hdl.handle.net/20.500.12418/26470
dc.identifier.volume31
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofThe Journal of oral implantology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAnimals; Biocompatible Materials; Bone Diseases; Bone Regeneration; Calcium Phosphates; Ceramics; Durapatite; Fibroblasts; Hydroxyapatites; Osteoblasts; Osteogenesis; Parietal Bone; Rats; Rats, Wistar; Surgical Flaps; Wound Healing; biomaterial; calcium phosphate; Ceraform; hydroxyapatite; animal; article; bone development; bone disease; bone regeneration; ceramics; fibroblast; osteoblast; pathology; pathophysiology; physiology; plastic surgery; rat; skull; Wistar rat; wound healing
dc.titleThe effect of a biphasic ceramic on calvarial bone regeneration in rats.
dc.typeArticle

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