Evaluation of Cerebral Oxygenation and Tissue Perfusion in Patients Ongoing Coronary Artery Surgery with Cardiopulmonary By-pass

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dc.contributor.authorAvcı, Onur
dc.contributor.authorGündoğdu, Oğuz
dc.date.accessioned2024-10-26T17:42:58Z
dc.date.available2024-10-26T17:42:58Z
dc.date.issued2019
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: We aimed to determine whether there is a correlation between perfusionparameters [Lactate (lac), venoarterial carbondioxide gradient (?pCO2), central venous oxygen saturation (ScVO2)] and the relationship between these parameters and cerebral oxygenation in normothermia (T2), hypothermia (T3) and re-warming (T4) periods in cardiopulmonary bypassprocedure (CPB). Material and Methods: Forty patients aged 19-78 years who were scheduled forelective coronary artery bypass surgery were included in the study. Mean arterial pressure (MAP),cerebral oxygenation (rSO2), periferic oxygen saturation (SpO2) values were recorded and by taking blood samples from arterial cannula and central venous catheter simultaneously; hematocrit(Htc), ?pCO2, lac, ScVO2, actual base excess (aBE), bicarbonate (HCO3) values were recorded in T1(after anesthesia induction and central venous catheterization), T2 (normothermia, 36oC, at the startof CPB), T3 (hypotermia, 32oC) and in T4 (at the end of CPB, rewarming, 36oC). Results: Between?pCO2-lac values, only positive correlation was found in T4 and there was no correlation betweenthem at other times. There was significant negative correlation between rSO2 and lac in T1, T3 andT4, but no significant correlation was found between rSO2-?pCO2 parameters at any time. The correlations of lac and ?pCO2 with cross-clamp and CPB durations were positive, whereas the correlations between ScVO2 and rSO2 with cross-clamp and CPB durations were negative. Conclusion:?pCO2 is not an early indicator of hypoperfusion in patients undergoing CPB in accordance withthe literature and the lactate level is a guiding parameter in reporting the perfusion status. We recommend the intraoperative use of cerebral oximetry to prevent the brain from being affected by hypoperfusion during CPB and to prevent postoperative neurocognitive disorders in patients.
dc.identifier.doi10.5336/cardiosci.2019-65779
dc.identifier.endpage115
dc.identifier.issn1306-7656
dc.identifier.issn2146-9032
dc.identifier.issue2
dc.identifier.startpage109
dc.identifier.trdizinid334434
dc.identifier.urihttps://doi.org/10.5336/cardiosci.2019-65779
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/334434
dc.identifier.urihttps://hdl.handle.net/20.500.12418/24950
dc.identifier.volume31
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürkiye Klinikleri Cardiovascular Sciences
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPeriferik Damar Hastalıkları
dc.subjectKalp ve Kalp Damar Sistemi
dc.titleEvaluation of Cerebral Oxygenation and Tissue Perfusion in Patients Ongoing Coronary Artery Surgery with Cardiopulmonary By-pass
dc.typeArticle

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