Examination of Biological Activity of Passiflora edulis (Çarkıfelek) Extract via Phytochemical Analysis

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dc.contributor.authorTunc, Tutku
dc.contributor.authorSümer, Zeynep
dc.contributor.authorÖksüz, Kerim Emre
dc.contributor.authorÖksüz, Kerim Emre
dc.date.accessioned2025-05-04T16:39:53Z
dc.date.available2025-05-04T16:39:53Z
dc.date.issued2024
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractIn recent years, the use of medicinal plants as sources of drugs or herbal extracts has been of great importance. Passiflora edulis is nowadays widely studied for its antimicrobial, anticancer, and antioxidant potential. Therefore, this study aimed to determine the phytochemical structure of ethanol extract of P. edulis leaves and to investigate its biological properties such as antimicrobial and anticancer activities. The ethanol extract of P. edulis leaves was obtained and analyzed by GC-MS. The antimicrobial activity of P. edulis leaf extract was determined by MIC test. XTT method was used to determine the antiproliferative activity. In the phytochemical analysis of P. edulis extract, dodecanoic acid, tetradecanoic acid, and n-hexadecanoic acid were found the most. The antimicrobial effect of P. edulis leaf extract was found against pathogenic microorganisms. In addition, P. edulis leaf extract was found to have high anticancer activity against OvCar and MCF-7 cell lines, while it had the highest effect on the PC-3 cell line. It is thought that the effectiveness of this antiproliferative and antimicrobial activity is related to the secondary metabolites determined by GC-MS analysis
dc.identifier.doi10.17776/csj.1519699
dc.identifier.endpage470
dc.identifier.issn2587-2680
dc.identifier.issn2587-246X
dc.identifier.issue3
dc.identifier.startpage465
dc.identifier.trdizinid1269074
dc.identifier.urihttps://doi.org/10.17776/csj.1519699
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1269074
dc.identifier.urihttps://hdl.handle.net/20.500.12418/34909
dc.identifier.volume45
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofCumhuriyet Science Journal
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR_20250504
dc.subjectPassiflora edulis
dc.subjectAntimicrobial effect
dc.subjectAntiproliferative effect
dc.subjectSecondary metabolite
dc.subjectDodecanoic acid
dc.titleExamination of Biological Activity of Passiflora edulis (Çarkıfelek) Extract via Phytochemical Analysis
dc.typeArticle

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