Evaluation of a sternum dehiscence reconstruction graft on an animal model

dc.contributor.authorKasımzade, Ferit
dc.contributor.authorAda, Fatih
dc.contributor.authorKarataş, Özhan
dc.date.accessioned2024-10-26T17:44:03Z
dc.date.available2024-10-26T17:44:03Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractSternum dehiscence occurring after surgeries requiring median incision of the sternum remains a current problem. New materials are needed to prevent or reduce the risk\rof developing sternum dehiscence. In this study, the effects of extracellular matrix (ECM)-like sternum dehiscence graft in a rabbit model were investigated. A total of\r24 rabbits in three groups were used in the study. There were eight rabbits in each group. The first group was the control group, the second group was the conventional\rclosure method, and the third group was the sternum closure graft group. Median sternotomy was applied to the rabbits in the second and third groups. Animals were\rsacrificed 4 weeks after surgery and sternum samples were taken. Sternum samples taken from untreated animals had normal histological appearance. Cartilage formation\rand fibrocyte-fibroblast activity were mild in the conventional surgery group, while moderate in the reconstruction graft group. It has been shown histopathologically that\rsternum closure graft accelerates bone healing (P= 0.015). It is obvious that if this graft is used clinically, it will reduce the incidence of sternum dehiscence.
dc.identifier.doi10.5455/medscience.2021.10.356
dc.identifier.endpage602
dc.identifier.issn2147-0634
dc.identifier.issue2
dc.identifier.startpage598
dc.identifier.trdizinid529743
dc.identifier.urihttps://doi.org/10.5455/medscience.2021.10.356
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/529743
dc.identifier.urihttps://hdl.handle.net/20.500.12418/25081
dc.identifier.volume11
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleEvaluation of a sternum dehiscence reconstruction graft on an animal model
dc.typeArticle

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