The Relationship of Inflammation Parameters with Obstruction in Coronary Artery Ectasia

Basit Öğe Kaydı
dc.contributor.authorÇerik, İdris Buğra
dc.contributor.authorDindaş, Ferhat
dc.contributor.authorÖmür, Sefa
dc.contributor.authorYenerçağ, Mustafa
dc.date.accessioned2024-10-26T17:42:27Z
dc.date.available2024-10-26T17:42:27Z
dc.date.issued2021
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractBackground: Coronary artery ectasia (CAE) is a coronary artery disease that can progress in a wide clinical spectrum, from asymptomatic cases to stable angina pectoris or acute coronary syndrome. CAE can present with an acute coronary syndrome without an obstructive lesion. Although many studies comparing isolated CAE with normal coronary arteries and coronary artery disease, CAE patients with obstructive type lesions (obstructive CAE) have never been evaluated. In this study, we aimed to compare obstructive CAE patients and isolated CAE patients in terms of various inflammatory parameters. Materials and Methods: A total of 190 patients were enrolled, including 95 obstructive CAE patients and 95 age and sex-matched isolated CAE patients. All participants were evaluated in the study consisted of patients admitted to the emergency department and diagnosed with NSTE-ACS. Systemic inflammatory parameters such as Platelet/lymphocyte ratio (PLR), Neutrophil/lymphocyte ratio (NLR), Monocyte/HDL ratio, CRP and sedimentation of the patients, were compared between two groups. Results: CRP value was found significantly higher in obstructive CAE, compared to isolated CAE [5.5 (3.0- 9.0) mg/L, 4.0 (3.0-6.0) mg/L (P=0.003) respectively]. PLR value was found significantly higher in obstructive CAE compared to isolated CAE [143±76, 120±45 (p=0.015) respectively]. In multivariable logistic regression analysis, only CRP was an independent predictor of obstruction in CAE [OR:1.075 (1.011-1.142), p=0.021]. Conclusions: To the best of our knowledge, this study is the first to evaluate the effects of obstructive lesions on inflammatory parameters in patients with CAE presenting with acute coronary syndrome. We have shown that systemic inflammation is increased in the presence of obstructive coronary artery disease in CAE patients.
dc.identifier.doi10.35440/hutfd.833532
dc.identifier.endpage7
dc.identifier.issn1304-9623
dc.identifier.issn1309-4025
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.trdizinid472865
dc.identifier.urihttps://doi.org/10.35440/hutfd.833532
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/472865
dc.identifier.urihttps://hdl.handle.net/20.500.12418/24638
dc.identifier.volume18
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofHarran Üniversitesi Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectInflammation
dc.subjectmyocardial infarction
dc.subjectcoronary artery ectasia
dc.titleThe Relationship of Inflammation Parameters with Obstruction in Coronary Artery Ectasia
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu