Evaluation of antimicrobial susceptibility and clonal relationships of acinetobacter baumannii isolates produced from patients in a university hospital

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dc.contributor.authorDurukan, Seher
dc.contributor.authorÇelik, Cem
dc.contributor.authorKafa, Ayşe Hümeyra Taşkın
dc.contributor.authorHasbek, Mürşit
dc.date.accessioned2024-10-26T17:54:20Z
dc.date.available2024-10-26T17:54:20Z
dc.date.issued2021
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: Acinetobacter baumannii is one of the most important causes of hospital-acquired infections that cause increased mortality and morbidity in hospital settings and intensive care units. In this study, it was aimed to interpret the clonal relationships of A.baumannii isolates by evaluating them together with epidemiological data. Material and Method: A total of 179 A. baumannii isolates produced from various samples of inpatients in Intensive Care Units and different wards in Sivas Cumhuriyet University Application and Research Hospital between 2012-2018 were included in the study. Antimicrobial susceptibilities of A.baumannii isolates were obtained from the laboratory data analysis system. From these isolates, clonal relationships of 132 DNA samples, which were found to be suitable for quality and quantitation were evaluated by repetitive extragenic palindromic (rep-PCR) method. Results: As a result of the examination of clonal relations, 24 cluster belonging to A. baumannii were determined. Within the groups, cluster 8, cluster 15, and cluster 24 were identified as dominant groups. Intensive care units stand out as the most intensive services in clusters. Conclusion: In this study, it was established that A. baumannii clusters continued to exist in our hospital within the specified years. Especially if precautions are not taken, it should be kept in mind that resistant epidemic clusters can remain in the hospital environment for long years and can be transported from patient to patient. Therefore, to prevent the spread of Acinetobacter infections in hospital settings, hospitals should have continuously updated surveillance programs, and infection control protocols should be strictly implemented and supervised. © 2021, Nobelmedicus. All rights reserved.
dc.identifier.endpage47
dc.identifier.issn1305-2381
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85106173347
dc.identifier.scopusqualityQ4
dc.identifier.startpage39
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27144
dc.identifier.volume17
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherNobelmedicus
dc.relation.ispartofNobel Medicus
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcinetobacter baumannii; Clonal relationship; Nosocomial infection
dc.titleEvaluation of antimicrobial susceptibility and clonal relationships of acinetobacter baumannii isolates produced from patients in a university hospital
dc.title.alternativeBir üniversite hastanesinde yatan hastalardan üretilen acinetobacter baumannii izolatlarininin antimikrobiyal duyarliliklari ve klonal ilişkilerinin değerlendirilmesi
dc.typeArticle

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