Evaluation of a gold nanocomposite hyaluronic acid-based adhesion barrier withantibacterial properties in an animal model

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dc.contributor.authorKasımzade, Ferit
dc.contributor.authorAda, Fatih
dc.contributor.authorÖzkaraca, Mustafa
dc.contributor.authorMendil, Ali Sefa
dc.date.accessioned2024-10-26T17:44:10Z
dc.date.available2024-10-26T17:44:10Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjectives: In this study, the effects of a gold nanocomposite hyaluronic acid-based adhesion barrier were evaluated in an animal model.\rMaterials and methods: In our study, a total of 42 rats in seven groups, with six rats in each group, were evaluated. The groups were\restablished according to the application of an adhesion barrier. In the first, second, and third groups, an adhesion barrier was applied by\rstandard median laparotomy in the first, second, and fourth weeks, respectively. The fourth, fifth, and sixth groups underwent the same\rprocedure in the first, second, and fourth weeks; however, no adhesion barrier was applied to these groups. The seventh group was the\rcontrol group, and no treatment was performed in this group.\rResults: There was no significant difference in the formation of inflammatory cells and fibrous tissue between the groups that underwent\rlaparotomy in the first and second weeks with and without the adhesion barrier (p>0.05). However, both low inflammatory cells (p<0.05)\rand low fibrous tissue (p<0.05) were evaluated in favor of the adhesion barrier group operated at the fourth week.\rConclusion: A gold nanocomposite hyaluronic acid-based adhesion barrier prevents adhesion, particularly in the long term. However, the\rresults need to be supported by clinical studies.
dc.identifier.doi10.5606/e-cvsi.2022.1281
dc.identifier.endpage110
dc.identifier.issn2148-9211
dc.identifier.issue2
dc.identifier.startpage104
dc.identifier.trdizinid534647
dc.identifier.urihttps://doi.org/10.5606/e-cvsi.2022.1281
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/534647
dc.identifier.urihttps://hdl.handle.net/20.500.12418/25147
dc.identifier.volume9
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofCardiovascular surgery and interventions
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleEvaluation of a gold nanocomposite hyaluronic acid-based adhesion barrier withantibacterial properties in an animal model
dc.typeArticle

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