Comparison of postoperative analgesia methods in lower abdominal surgery

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dc.contributor.authorGürsoy, Sinan
dc.contributor.authorKaygusuz, Kenan
dc.contributor.authorDemirel, Yeltekin
dc.contributor.authorDuran, Bülent
dc.contributor.authorKafali, Haluk
dc.contributor.authorMimaro?lu, Caner
dc.date.accessioned2024-10-26T17:53:26Z
dc.date.available2024-10-26T17:53:26Z
dc.date.issued2006
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: The present study aimed to determine the advantage and disadvantage of different postoperative analgesia methods in patients undergoing cesarean section or hysterectomy under general anesthesia. Material and methods: Following ethics committee approval and patient informed consents, 120 patients were recruited from the ASA I-III groups. Patients were divided randomly into 6 groups. IM-D group received intramuscular diclofenac sodium (75 mg) every 12 hours. IM-ME group received intramuscular meperidine (1 mg kg -1) every 6 hours. IM-DME group received intramuscular meperidine (1 mg kg-1)-diclofenac sodium (75 mg) combination every 12 hours. EP-MO group received epidural morphine (bolus of 3 mg and 0.06 mg mL-1 morphine; 6 ml h-1) infusion. EP-MOB group received epidural infusion of morphine-bupivacaine combination (bolus of 2 mg morphine + 35 mg bupivacaine combination, 2 mg ml-1 bupivacaine + 0.03 mg mL-1 morphine combination; 6 ml h-1). IV-MO group received intravenous morphine via patient-controlled analgesia (loading dose of 3 mg, bolus of 1 mg and 20 minutes lockout interval). Heart rate, mean arterial pressure, SpO 2, pain and sedation levels were recorded at 2, 6, 12, 24 and 48 hours. Furthermore, additional analgesic consumption and side effects were also recorded. Results: Effective analgesia was in groups IM-DME, EP-MO, EP-MOB, and IV-MO. However, the lowest pain scores were obtained in groups EP-MO and EP-MOB. Sedation scores were higher in groups EP-MO and IV-MO. While the highest additional analgesic consumption was in groups IM-D and IM-ME, there was no additional analgesic consumption in groups EP-MO, EP-MOB and IV-MO. Side effects were not observed in any groups that required treatment. The highest incidence of side effects were in group IV-MO whereas the lowest incidence of side effects were observed in groups IM-DME and EP-MOB. Conclusion: While there was effective analgesia in groups IM-DME, EP-MO, EP-MOB, and IV-MO, IM diclofenac + meperidine combination and epidural bupivacaine + morphine combination seemed more advantageous when the side effects were considered. Copyright © 2006 by Türkiye Klinikleri.
dc.identifier.endpage152
dc.identifier.issn1300-0292
dc.identifier.issue2
dc.identifier.scopus2-s2.0-33646550881
dc.identifier.scopusqualityQ4
dc.identifier.startpage146
dc.identifier.urihttps://hdl.handle.net/20.500.12418/26945
dc.identifier.volume26
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherTurkiye Klinikleri
dc.relation.ispartofTurkiye Klinikleri Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAnalgesia; Diclofenac; Epidural; Morphine; Surgery
dc.titleComparison of postoperative analgesia methods in lower abdominal surgery
dc.title.alternativeAlt batin cerrahilerinde postoperatif analjezi yöntemlerinin karşilaştirilmasi
dc.typeArticle

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