Relation of neutrophil/lymphocyte ratio to resistant hypertension

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dc.contributor.authorDağlı, Necati
dc.contributor.authorDoğdu, Orhan
dc.contributor.authorŞenarslan, Ömer
dc.contributor.authorYücel, Hasan
dc.contributor.authorKaya, Hakki
dc.contributor.authorAkpek, Mahmut
dc.contributor.authorEriten, Semih
dc.date.accessioned2024-10-26T17:37:53Z
dc.date.available2024-10-26T17:37:53Z
dc.date.issued2016
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjectives. Resistant hypertension has unfavourable effects on cardiovascular and other systems. The aim of this study was to investigate the association of neutrophil/lymphocyte (N/L) ratio and resistant hypertension. Methods. A total of 140 patients were included in the study. Ambulatory 24-hour blood pressure monitoring, transthoracic echocardiography and blood sample analyzing were performed in all patients. There were 60 patients with resistant hypertension group (mean age=55.1±9.7 years) and 80 patients with non-resistant hypertension group (mean age=56.8±14.1 years). Results. Mean neutrophil levels were significantly higher in resistant hypertension group (71.7±6.1% vs. 65.9±5.4%, p<0.001), while lymphocyte levels were significantly higher in non-resistant hypertension group (22±4.7% vs. 17.5±4.1%, p<0.001). N/L ratio was significantly higher in resistant hypertension group (4.3±1.2 vs. 3.1±0.9, p<0.001). In multivariate analysis, diabetes mellitus (odds ratio [OR]=2.857; 95% confidence interval [CI], 1.349-6.053; p=0.006), N/L ratio (OR=2.699; 95% CI, 1.821-4.002; p<0.001) and obesity (OR=3.429; 95% CI, 1.675-7.019; p=0.001) were independent predictors of resistant hypertension. Conclusion. The N/L ratio, which is cheaply and easily measurable laboratory data, is independently associated with resistant hypertension. 
dc.identifier.doi10.18621/eurj.2016.5000185856
dc.identifier.endpage218
dc.identifier.issn2149-3189
dc.identifier.issue3
dc.identifier.startpage211
dc.identifier.trdizinid1153984
dc.identifier.urihttps://doi.org/10.18621/eurj.2016.5000185856
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1153984
dc.identifier.urihttps://hdl.handle.net/20.500.12418/23689
dc.identifier.volume2
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofThe European Research Journal
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNeutrophil/lymphocyte ratio
dc.subjectambulatory blood pressure monitoring
dc.subjectResistant hypertension
dc.titleRelation of neutrophil/lymphocyte ratio to resistant hypertension
dc.typeArticle

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