Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye

dc.contributor.authorDemir, Tuğba
dc.contributor.authorAğaoğlu, Sema
dc.date.accessioned2024-10-26T17:38:13Z
dc.date.available2024-10-26T17:38:13Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractThe objectives of the study were to determine the aflatoxin M1 (AFM1) content in ınfant formula samples in Türkiye and to assess the risk of infants’ exposure to aflatoxins food contamination. A total number of 72 samples of infant formulas (premature, hipoallergenic, 0-6, 6-9,9-12 and 12-36 months) were analyzed for the presence of AFM1 using the Enzyme Linked Immunosorbent Assay (ELISA) method. 49% of the samples (35 samples) were contaminated with AFM1 and the group most highly contaminated with AFM1 was infant formulas 12-36 (8 samples) months. In addition, this study aimed at evaluating AFM1 levels especially above international (European Commission) (0.025 ?g/kg) and local (Türkiye Food Codex Regulation) (0.025 ?g/kg) standards and cancer risks associated with the ingestion of infant formula sampled from Türkiye. Five samples of infant formula had AFM1 concentration above maximum allowable concentration according to the standards. Risk assessments of AFM1 for infants ranged between 0.002- 0.035 ng/kg bw/day and >100.000–5263.15 respectively for Estimated Daily Intake (EDI), and Margin of Exposure (MOE). The riskiest group was determined in the 9-12 months samples. Results of our study indicate the high risk of infants’ exposure, who are at the early stage of development and vulnerable to toxic contaminants.
dc.identifier.doi10.24925/turjaf.v11i2.396-402.5805
dc.identifier.endpage402
dc.identifier.issn2148-127X
dc.identifier.issue2
dc.identifier.startpage396
dc.identifier.trdizinid1172224
dc.identifier.urihttps://doi.org/10.24925/turjaf.v11i2.396-402.5805
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1172224
dc.identifier.urihttps://hdl.handle.net/20.500.12418/23909
dc.identifier.volume11
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürk Tarım - Gıda Bilim ve Teknoloji dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleExposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye
dc.typeArticle

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